SCHEMBL8772360

SCHEMBL8772360

Oc1c(Cc2ccccc2)cc(Cc2cc(Cc3ccccc3)c(O)c3ccccc23)c2ccccc12

nearest known ligand 0.71

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HMGB1 P09429 1/20 0.56
CXCL12 P48061 1/20 0.56
BCL2 P10415 1/20 0.53
BCL2L1 Q07817 1/20 0.53
PTPN2 P17706 1/20 0.49
PTPN1 P18031 1/20 0.49
PTPN6 P29350 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19039045 0.87 KEAP1 (0.53)
SCHEMBL11070082 0.85 BCL2 (0.64) BCL2BCL2L1
SCHEMBL8930618 0.84 BCL2 (0.61) BCL2BCL2L1PTPN2PTPN1PTPN6
SCHEMBL29083885 0.82 HMGB1 (0.50) HMGB1CXCL12BCL2BCL2L1
SCHEMBL8772263 0.81 LMNA (0.53) BCL2BCL2L1
SCHEMBL9747950 0.81 BCL2 (0.50) BCL2BCL2L1
SCHEMBL9748771 0.81 PTPN1 (0.51) BCL2BCL2L1PTPN1
SCHEMBL19990808 0.79 BCL2 (0.54) BCL2BCL2L1
SCHEMBL5663542 0.79 PTPN1 (0.47) BCL2BCL2L1PTPN2PTPN1PTPN6
SCHEMBL9618995 0.79 HMGB1 (0.84) HMGB1CXCL12PTPN2PTPN1PTPN6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0461621-B1 Image forming method CANON KK (JP) 1997-10-15 EP disclosed
EP-0412851-B1 Photosensitive member and multi-color image forming method CANON KK (JP) 1995-06-14 EP disclosed
EP-0363790-B1 Image forming method and image forming medium CANON KK (JP) 1995-05-31 EP disclosed
US-5393638-A Image forming method CANON KABUSHIKI KAISHA (JP) 1995-02-28 US disclosed
US-5374496-A Image forming method CANON KABUSHIKI KAISHA (JP) 1994-12-20 US disclosed
US-5187041-A IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS CANON KABUSHIKI KAISHA (JP) 1993-02-16 US disclosed
US-5171657-A Containing photopolymerizable monomer CANON KABUSHIKI KAISHA (JP) 1992-12-15 US disclosed
EP-0461621-A2 Image forming method CANON KABUSHIKI KAISHA (JP) 1991-12-18 EP disclosed
EP-0453125-A2 Image forming method and image forming apparatus CANON KABUSHIKI KAISHA (JP) 1991-10-23 EP disclosed