Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PTAFR | P25105 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PDE1A | P54750 | 1/20 | 0.42 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071229 | 0.80 | PDE3B (0.67) | ALDH1A1KDM4EHSD17B10KMT2AMEN1 | |
| SCHEMBL11066631 | 0.78 | PDE3B (0.63) | ALDH1A1KDM4EHSD17B10KMT2AMEN1 | |
| SCHEMBL11065347 | 0.78 | PDE3B (0.65) | ALDH1A1KDM4EHSD17B10KMT2AMEN1 | |
| SCHEMBL11317575 | 0.77 | PDE3B (0.49) | ALDH1A1KDM4EHSD17B10KMT2AMEN1 | |
| SCHEMBL11278744 | 0.70 | CA12 (0.42) | KMT2AMEN1PDE3BPDE3ACYP3A4 | |
| SCHEMBL11282436 | 0.70 | CYSLTR2 (0.44) | PDE3BPDE3A | |
| SCHEMBL11064318 | 0.69 | PDE3B (0.67) | ALDH1A1KMT2AMEN1PDE3BPDE3A | |
| SCHEMBL9820774 | 0.69 | MCHR1 (0.49) | KMT2AMEN1PDE5ACYP3A4LMNA | |
| SCHEMBL11062114 | 0.68 | PDE3B (0.60) | ALDH1A1KDM4EHSD17B10KMT2AMEN1 | |
| SCHEMBL10064553 | 0.68 | MCHR1 (0.48) | PDE3BPDE3ACYP1A2CYP2C19GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435404-A | ANTICOAGULANTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-03-06 | — | — | US | disclosed |