Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11226733 | 1.00 | SHBG (0.50) | SHBGTSHRALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL8330847 | 0.86 | SHBG (0.61) | SHBGTSHRALDH1A1L3MBTL1KDM4E | |
| SCHEMBL8330418 | 0.85 | SHBG (0.44) | SHBGTSHRALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL16732011 | 0.84 | SHBG (0.58) | SHBGTSHRALDH1A1L3MBTL1 | |
| SCHEMBL8784689 | 0.81 | SHBG (0.55) | SHBGTSHRALDH1A1L3MBTL1KDM4E | |
| SCHEMBL16732332 | 0.78 | SHBG (0.55) | SHBGTSHRALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL16732291 | 0.78 | ALDH1A1 (0.48) | SHBGTSHRALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL27406371 | 0.78 | ALDH1A1 (0.48) | SHBGTSHRALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL16732209 | 0.77 | ALDH1A1 (0.43) | SHBGTSHRALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL16783913 | 0.76 | SHBG (0.52) | SHBGTSHRALDH1A1NPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4430339-A | PROPHYLAXIS, METABOLISM, GLUCOSE, FATS, HYPOGLYCEMIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1984-02-07 | — | — | US | disclosed |
| WO-1982000822-A1 | SUBSTITUTED OXIRANECARBOXYLIC ACIDS,THEIR PREPARATION AND THEIR USE AS MEDICAMENTS | EISTETTER K | 1982-03-18 | — | — | WO | disclosed |