Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 3/20 | 0.63 |
| ▸ | APP | P05067 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | XDH | P47989 | 1/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.47 |
| ▸ | TUBB | P07437 | 2/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9520208 | 0.90 | IAPP (0.61) | IAPPAPPRAB9AKMT2ANPC1 | |
| SCHEMBL9520212 | 0.90 | IAPP (0.61) | IAPPAPPRAB9AKMT2ANPC1 | |
| SCHEMBL3395878 | 0.85 | ALDH1A1 (0.66) | IAPPAPPRAB9AKMT2ANPC1 | |
| SCHEMBL3395879 | 0.85 | ALDH1A1 (0.66) | IAPPAPPRAB9AKMT2ANPC1 | |
| SCHEMBL11067022 | 0.83 | IAPP (0.58) | IAPPAPPRAB9AKMT2AESR1 | |
| SCHEMBL11077596 | 0.83 | IAPP (0.57) | IAPPRAB9AKMT2AESR1NPC1 | |
| SCHEMBL27629789 | 0.82 | IAPP (0.69) | IAPPAPPESR1ABCG2 | |
| SCHEMBL3399802 | 0.82 | IAPP (0.65) | IAPPAPPRAB9AKMT2ANPC1 | |
| SCHEMBL3399806 | 0.82 | IAPP (0.65) | IAPPAPPRAB9AKMT2ANPC1 | |
| SCHEMBL861926 | 0.80 | ALDH1A1 (0.64) | IAPPAPPRAB9AKMT2AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4467112-A | REACTING P-FORMYLBENZOIC ACID OR ESTER WITH KETONE, HYDROGENATION AND REDUCTION OF INTERMEDIATES | KAWASAKI KASEI CHEMICALS LTD. (JP) | 1984-08-21 | — | — | US | disclosed |