Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11054345 | 0.86 | GRIK1 (0.66) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1275812 | 0.80 | KMT2A (0.72) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11072641 | 0.80 | KMT2A (0.73) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL10514431 | 0.78 | RAB9A (0.69) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL24004522 | 0.77 | GRIK1 (0.61) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11504808 | 0.76 | NOX1 (0.77) | NOX1RAB9ANPC1SMN1; SMN2THRB | |
| SCHEMBL16566574 | 0.75 | ALDH1A1 (0.65) | KMT2AMEN1ALDH1A1MAPT | |
| SCHEMBL10488934 | 0.74 | MAPT (0.76) | NOX1RAB9ANPC1SMN1; SMN2THRB | |
| SCHEMBL8491865 | 0.74 | RAB9A (1.00) | NOX1KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL10393959 | 0.74 | KMT2A (0.64) | KMT2AMEN1RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4461821-A | Photoconductive compositions and electrophotographic photosensitive materials comprising an organic photoconductor and a thiourea compound | FUJI PHOTO FILM CO., LTD. (JP) | 1984-07-24 | — | — | US | disclosed |