Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 7/20 | 0.45 |
| ▸ | CA9 | Q16790 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11069439 | 0.89 | NPC1 (0.46) | CA12CA9KDM4ENPC1ALDH1A1 | |
| SCHEMBL11076877 | 0.86 | KDM4E (0.45) | CA12CA9KDM4ENPC1ALDH1A1 | |
| SCHEMBL11073912 | 0.85 | CA12 (0.48) | CA12CA9KDM4ENPC1ALDH1A1 | |
| SCHEMBL11082145 | 0.85 | CA12 (0.36) | CA12CA9KDM4ENPC1ALDH1A1 | |
| SCHEMBL11076516 | 0.83 | CA2 (0.49) | CA12CA9KDM4ENPC1ALDH1A1 | |
| SCHEMBL11327732 | 0.82 | CA2 (0.48) | CA12CA9KDM4ENPC1ALDH1A1 | |
| SCHEMBL11068028 | 0.81 | CA2 (0.47) | CA12CA9KDM4ENPC1ALDH1A1 | |
| SCHEMBL11072085 | 0.81 | CA2 (0.47) | CA12CA9KDM4ENPC1ALDH1A1 | |
| SCHEMBL11077549 | 0.81 | CA2 (0.47) | CA12CA9KDM4ENPC1ALDH1A1 | |
| Monosulfuron SCHEMBL29350477 | 0.80 | NPSR1 (0.49) | KDM4ENPC1ALDH1A1CA2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0023140-B1 | HERBICIDAL SULFONAMIDES, PREPARATION AND USE THEREOF, AND COMPOSITIONS CONTAINING THEM | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-10-31 | — | — | EP | claimed |