SCHEMBL11076877

SCHEMBL11076877

Cc1nc(NC(=O)NS(=O)(=O)c2ccccc2C(=O)O)ncc1Cl

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.45
NPC1 O15118 1/20 0.45
ALDH1A1 P00352 1/20 0.45
CA12 O43570 7/20 0.45
CA9 Q16790 7/20 0.45
CA1 P00915 3/20 0.45
CA2 P00918 3/20 0.45
MMP1 P03956 1/20 0.43
MMP2 P08253 1/20 0.43
MMP9 P14780 1/20 0.43
MMP8 P22894 1/20 0.43
MMP13 P45452 1/20 0.43
FBP1 P09467 1/20 0.41
F2 P00734 1/20 0.41
PRSS1 P07477 1/20 0.41
PRSS2 P07478 1/20 0.41
PRSS3 P35030 1/20 0.41
MAPT P10636 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11076843 0.89 NPC1 (0.46) KDM4ENPC1ALDH1A1CA12CA9
SCHEMBL11072085 0.86 CA2 (0.47) KDM4ENPC1ALDH1A1CA12CA9
SCHEMBL11070561 0.86 CA12 (0.45) KDM4ENPC1ALDH1A1CA12CA9
SCHEMBL11076516 0.83 CA2 (0.49) KDM4ENPC1ALDH1A1CA12CA9
SCHEMBL11052495 0.83 CA1 (0.49) KDM4ENPC1ALDH1A1CA12CA9
SCHEMBL11327732 0.82 CA2 (0.48) KDM4ENPC1ALDH1A1CA12CA9
SCHEMBL11077549 0.81 CA2 (0.47) KDM4ENPC1ALDH1A1CA12CA9
SCHEMBL11068028 0.81 CA2 (0.47) KDM4ENPC1ALDH1A1CA12CA9
Monosulfuron SCHEMBL29350477 0.81 NPSR1 (0.49) KDM4ENPC1ALDH1A1CA1CA2
SCHEMBL11073912 0.80 CA12 (0.48) KDM4ENPC1ALDH1A1CA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0023140-B1 HERBICIDAL SULFONAMIDES, PREPARATION AND USE THEREOF, AND COMPOSITIONS CONTAINING THEM E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-10-31 EP claimed