Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.44 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.43 |
| ▸ | PGK1 | P00558 | 3/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11115371 | 0.81 | FERMT2 (0.47) | ALDH1A1KDM4EGAAMAPTHPGD | |
| SCHEMBL23144718 | 0.81 | LPAR1 (0.44) | LMNAALDH1A1KDM4EGAAMAPT | |
| SCHEMBL14258683 | 0.79 | ACHE (0.52) | LMNAALDH1A1KDM4EGAAMAPT | |
| SCHEMBL3372005 | 0.79 | ALDH1A1 (0.57) | ALDH1A1KDM4EGAAMAPTHPGD | |
| SCHEMBL9281838 | 0.79 | APP (0.51) | LMNAALDH1A1KDM4EGAATSHR | |
| SCHEMBL24460022 | 0.78 | ALDH1A1 (0.57) | LMNAALDH1A1KDM4EGAAMAPT | |
| SCHEMBL3789681 | 0.78 | SMN1; SMN2 (0.44) | LMNAALDH1A1KDM4EGAAMAPT | |
| SCHEMBL3717227 | 0.78 | PDE4B (0.41) | LMNAALDH1A1KDM4EGAAMAPT | |
| SCHEMBL14453287 | 0.78 | MAPT (0.52) | LMNAALDH1A1KDM4EGAAMAPT | |
| SCHEMBL11410073 | 0.77 | LPAR1 (0.49) | LMNAALDH1A1KDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |