Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 9/20 | 0.74 |
| ▸ | AR | P10275 | 6/20 | 0.74 |
| ▸ | ABCB11 | O95342 | 4/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.62 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | HTR1A | P08908 | 1/20 | 0.62 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.53 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11127170 | 1.00 | PGR (0.74) | PGRARABCB11CYP3A4NR3C1 | |
| SCHEMBL11127550 | 1.00 | PGR (0.74) | PGRARABCB11CYP3A4NR3C1 | |
| SCHEMBL11127169 | 1.00 | PGR (0.74) | PGRARABCB11CYP3A4NR3C1 | |
| SCHEMBL11262672 | 1.00 | PGR (0.74) | PGRARABCB11CYP3A4NR3C1 | |
| SCHEMBL11126579 | 0.92 | PGR (0.72) | PGRARABCB11CYP3A4NR3C1 | |
| SCHEMBL11236322 | 0.92 | PGR (0.72) | PGRARABCB11CYP3A4NR3C1 | |
| SCHEMBL11413999 | 0.92 | ABCB11 (0.79) | PGRARABCB11CYP3A4NR3C1 | |
| SCHEMBL22171557 | 0.92 | ABCB11 (0.79) | PGRARABCB11CYP3A4NR3C1 | |
| SCHEMBL11236326 | 0.92 | PGR (0.72) | PGRARABCB11CYP3A4NR3C1 | |
| SCHEMBL11124571 | 0.92 | ABCB11 (0.79) | PGRARABCB11CYP3A4NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4478818-A | Ocular preparation housing steroid in two different therapeutic forms | ALZA CORPORATION (US) | 1984-10-23 | — | — | US | claimed |