Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.54 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.48 |
| ▸ | SCN1A | P35498 | 2/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11067472 | 0.85 | KCNH2 (0.54) | KCNH2SLC18A3ABCB1SCN1ASCN5A | |
| SCHEMBL10570340 | 0.85 | MAPT (0.59) | ABCB1 | |
| SCHEMBL11072146 | 0.81 | KCNH2 (0.48) | KCNH2SLC18A3ABCB1SCN1ASCN5A | |
| SCHEMBL11071842 | 0.80 | SLC18A3 (0.48) | KCNH2SLC18A3LMNACHRM2CHRM4 | |
| SCHEMBL11067922 | 0.79 | KCNH2 (0.49) | KCNH2SLC18A3ABCB1SCN1ASCN5A | |
| SCHEMBL11064811 | 0.79 | KCNH2 (0.53) | KCNH2SLC18A3ABCB1SCN1ASCN5A | |
| SCHEMBL11603165 | 0.75 | DRD4 (0.72) | KCNH2ADRB1LMNAALDH1A1DRD2 | |
| SCHEMBL11061136 | 0.75 | KCNH2 (0.56) | KCNH2ABCB1SCN1ASCN5ASCN9A | |
| SCHEMBL9122718 | 0.75 | HTR1A (0.53) | KCNH2SLC18A3ABCB1LMNANPY1R | |
| Hydrochloric Acid SCHEMBL11602209 | 0.74 | DRD4 (0.71) | KCNH2LMNAALDH1A1DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |