Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.54 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.49 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.49 |
| ▸ | SCN1A | P35498 | 2/20 | 0.48 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NPY1R | P25929 | 1/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071272 | 0.90 | DRD4 (0.45) | KCNH2SLC18A3DRD4 | |
| SCHEMBL11067922 | 0.88 | KCNH2 (0.49) | KCNH2ABCB1SLC18A3SCN1ASCN5A | |
| SCHEMBL11073897 | 0.87 | ABCB1 (0.62) | ABCB1ADRB2ADRB1ADRB3DRD4 | |
| SCHEMBL11061136 | 0.86 | KCNH2 (0.56) | KCNH2ABCB1SCN1ASCN5ASCN9A | |
| SCHEMBL11070643 | 0.85 | KCNH2 (0.54) | KCNH2ABCB1SLC18A3SCN1ASCN5A | |
| Oxalic Acid SCHEMBL11060455 | 0.85 | ABCB1 (0.61) | ABCB1ADRB2ADRB1ADRB3DRD4 | |
| SCHEMBL11064919 | 0.85 | ADRB2 (0.51) | KCNH2ABCB1SLC18A3SCN1ASCN5A | |
| SCHEMBL11067546 | 0.85 | KCNH2 (0.52) | KCNH2ABCB1SLC18A3SCN1ASCN5A | |
| SCHEMBL10569856 | 0.85 | MAPT (0.59) | ABCB1SCN1ASCN5ASCN9AADRB2 | |
| SCHEMBL11064811 | 0.84 | KCNH2 (0.53) | KCNH2ABCB1SLC18A3SCN1ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482560-A | Carbostyril derivatives, and antihistaminic agents containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-11-13 | — | — | US | disclosed |