Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGALS8 | O00214 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | HRAS | P01112 | 1/20 | 0.40 |
| ▸ | HK1 | P19367 | 1/20 | 0.40 |
| ▸ | HK2 | P52789 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8822976 | 1.00 | LGALS8 (0.46) | LGALS8SLC6A2CA1CA2CA9 | |
| SCHEMBL11302596 | 1.00 | LGALS8 (0.46) | LGALS8SLC6A2CA1CA2CA9 | |
| SCHEMBL21630079 | 0.92 | SLC6A2 (0.45) | LGALS8SLC6A2CA1CA2CA9 | |
| SCHEMBL7768969 | 0.89 | LGALS8 (0.51) | LGALS8SLC6A2CA1CA2CA9 | |
| SCHEMBL8823022 | 0.88 | LGALS8 (0.50) | LGALS8SLC6A2 | |
| SCHEMBL8537936 | 0.84 | LGALS8 (0.61) | LGALS8CA1CA2CA9HRAS | |
| SCHEMBL8537938 | 0.84 | LGALS8 (0.61) | LGALS8CA1CA2CA9HRAS | |
| SCHEMBL9238485 | 0.84 | LGALS8 (0.61) | LGALS8CA1CA2CA9HRAS | |
| SCHEMBL2003046 | 0.84 | LMNA (0.50) | LGALS8CA1CA2CA9 | |
| SCHEMBL25412287 | 0.82 | SLC6A2 (0.43) | LGALS8SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472573-A | ANTITUMOR, ANTILEUKEMIC | TANABE SEIYAKU CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |