Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 8/20 | 0.48 |
| ▸ | F2 | P00734 | 2/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.48 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.48 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.48 |
| ▸ | PLK1 | P53350 | 3/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19149750 | 0.81 | PLK1 (0.49) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL6018274 | 0.81 | PRSS1 (0.57) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL10423618 | 0.81 | PRSS1 (0.57) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL11345267 | 0.81 | PLK1 (0.49) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL10356667 | 0.79 | PRSS1 (0.56) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL11563861 | 0.79 | PLK1 (0.50) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL11558109 | 0.79 | PLK1 (0.50) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL11733794 | 0.79 | PLK1 (0.47) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL11564115 | 0.79 | PLK1 (0.50) | PRSS1F2PRSS2PRSS3TMPRSS6 | |
| SCHEMBL11557527 | 0.79 | PLK1 (0.50) | PRSS1F2PRSS2PRSS3TMPRSS6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4485105-A | Method of treating hyperlipidemia with 4-(monoalkylamino)benzoic acid amides | AMERICAN CYANAMID COMPANY (US) | 1984-11-27 | — | — | US | disclosed |
| US-4242273-A | ANTILIPEMIC AND ANTICHOLESTEROL AGENTS | AMERICAN CYANAMID COMPANY (US) | 1980-12-30 | — | — | US | disclosed |
| US-4136256-A | HYPOLIPIDEMIC, ANTIATHEROSCLEROTIC | AMERICAN CYANAMID COMPANY (US) | 1979-01-23 | — | — | US | disclosed |