Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 3/20 | 0.49 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11564115 | 0.87 | PLK1 (0.50) | PLK1HCAR3LMNASCN5ACYP1A2 | |
| SCHEMBL11565019 | 0.87 | PLK1 (0.50) | PLK1HCAR3LMNASCN5ACYP1A2 | |
| SCHEMBL11558109 | 0.87 | PLK1 (0.50) | PLK1HCAR3LMNASCN5ACYP1A2 | |
| SCHEMBL11563861 | 0.87 | PLK1 (0.50) | PLK1HCAR3LMNASCN5ACYP1A2 | |
| SCHEMBL11557527 | 0.87 | PLK1 (0.50) | PLK1HCAR3LMNASCN5ACYP1A2 | |
| SCHEMBL19149750 | 0.84 | PLK1 (0.49) | PLK1HCAR3LMNASCN5ACYP1A2 | |
| Cetaben SCHEMBL2112078 | 0.82 | HCAR3 (0.59) | PLK1HCAR3PRSS1F2PRSS2 | |
| SCHEMBL10534588 | 0.82 | HCAR3 (0.59) | PLK1HCAR3PRSS1F2PRSS2 | |
| SCHEMBL2309354 | 0.82 | HCAR3 (0.59) | PLK1HCAR3PRSS1F2PRSS2 | |
| SCHEMBL22398313 | 0.82 | HCAR3 (0.59) | PLK1HCAR3PRSS1F2PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4272546-A | ANTILIPEMIC, ANTIATHEROSCLEROTIC | AMERICAN CYANAMID COMPANY (US) | 1981-06-09 | — | — | US | disclosed |
| US-4254138-A | ANTILIPEMIC AGENTS AND ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-03-03 | — | — | US | disclosed |
| US-4196208-A | ANTILIPEMIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1980-04-01 | — | — | US | disclosed |