Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 3/20 | 0.50 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | HRH2 | P25021 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | SCN1A | P35498 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11557527 | 1.00 | PLK1 (0.50) | PLK1HCAR3LMNASCN5ACYP1A2 | |
| SCHEMBL11565019 | 1.00 | PLK1 (0.50) | PLK1HCAR3LMNASCN5ACYP1A2 | |
| SCHEMBL11563861 | 1.00 | PLK1 (0.50) | PLK1HCAR3LMNASCN5ACYP1A2 | |
| SCHEMBL11558109 | 1.00 | PLK1 (0.50) | PLK1HCAR3LMNASCN5ACYP1A2 | |
| SCHEMBL11304893 | 0.90 | SOAT2 (0.45) | PLK1CYP1A2CNR1MAPK1CYP3A4 | |
| SCHEMBL11304889 | 0.90 | SOAT2 (0.45) | PLK1CYP1A2CNR1MAPK1CYP3A4 | |
| SCHEMBL11558040 | 0.88 | PLK1 (0.47) | PLK1HCAR3LMNASCN5ACYP1A2 | |
| SCHEMBL11345267 | 0.87 | PLK1 (0.49) | PLK1HCAR3LMNASCN5ACYP1A2 | |
| SCHEMBL11563318 | 0.86 | PRSS1 (0.42) | PLK1MAPK1RAB9APRSS1F2 | |
| SCHEMBL19149750 | 0.85 | PLK1 (0.49) | PLK1HCAR3LMNASCN5ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154756-A | HYPOLIPIDEMIC AND ANTIATHEROSCLEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1979-05-15 | — | — | US | disclosed |