Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | HRH2 | P25021 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.53 |
| ▸ | HRH1 | P35367 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | SCN1A | P35498 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19149288 | 0.82 | PLK1 (0.52) | LMNASCN5ACYP1A2MAOACNR1 | |
| SCHEMBL10534588 | 0.82 | HCAR3 (0.59) | PLK1PRSS1F2PRSS2PRSS3 | |
| SCHEMBL6372015 | 0.82 | PLK1 (0.52) | LMNASCN5ACYP1A2MAOACNR1 | |
| Cetaben SCHEMBL2112078 | 0.82 | HCAR3 (0.59) | PLK1PRSS1F2PRSS2PRSS3 | |
| SCHEMBL11478101 | 0.82 | HCAR3 (0.59) | PLK1PRSS1F2PRSS2PRSS3 | |
| SCHEMBL6372020 | 0.82 | HCAR3 (0.59) | PLK1PRSS1F2PRSS2PRSS3 | |
| SCHEMBL11283832 | 0.82 | HCAR3 (0.59) | PLK1PRSS1F2PRSS2PRSS3 | |
| SCHEMBL10950807 | 0.82 | HCAR3 (0.59) | PLK1PRSS1F2PRSS2PRSS3 | |
| SCHEMBL22398313 | 0.82 | HCAR3 (0.59) | PLK1PRSS1F2PRSS2PRSS3 | |
| SCHEMBL11278167 | 0.82 | HCAR3 (0.59) | PLK1PRSS1F2PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4485105-A | Method of treating hyperlipidemia with 4-(monoalkylamino)benzoic acid amides | AMERICAN CYANAMID COMPANY (US) | 1984-11-27 | — | — | US | disclosed |
| US-4309553-A | HYPOLIPIDEMIC, ANTIATHEROSCLEROTIC | AMERICAN CYANAMID COMPANY (US) | 1982-01-05 | — | — | US | disclosed |
| US-4273785-A | ANTILIPEMIC AGENTS, ANTIATHEROSCEROTIC AGENTS | AMERICAN CYANAMID COMPANY (US) | 1981-06-16 | — | — | US | disclosed |
| US-4242273-A | ANTILIPEMIC AND ANTICHOLESTEROL AGENTS | AMERICAN CYANAMID COMPANY (US) | 1980-12-30 | — | — | US | disclosed |
| US-4136256-A | HYPOLIPIDEMIC, ANTIATHEROSCLEROTIC | AMERICAN CYANAMID COMPANY (US) | 1979-01-23 | — | — | US | disclosed |