Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11063743 | 0.76 | TOP2A (0.48) | ALDH1A1TSHRLMNAKDM4EUSP2 | |
| SCHEMBL27659662 | 0.74 | LMNA (0.56) | ALDH1A1TSHRLMNAKDM4EUSP2 | |
| SCHEMBL16715260 | 0.73 | MEN1 (0.58) | ALDH1A1TSHRLMNAKDM4EUSP2 | |
| SCHEMBL10757808 | 0.71 | ALDH1A1 (0.62) | ALDH1A1TSHRLMNAKDM4EUSP2 | |
| SCHEMBL4417699 | 0.70 | KDM4E (0.58) | ALDH1A1LMNAKDM4EPOLBHSD17B10 | |
| SCHEMBL3093811 | 0.68 | HSP90AA1 (0.67) | ALDH1A1TSHRLMNAKDM4EUSP2 | |
| SCHEMBL31428429 | 0.68 | ALDH1A1 (0.68) | ALDH1A1TSHRLMNAKDM4EUSP2 | |
| SCHEMBL31428463 | 0.68 | ALDH1A1 (0.61) | ALDH1A1TSHRLMNAKDM4EUSP2 | |
| SCHEMBL12301110 | 0.68 | TSHR (0.48) | ALDH1A1TSHRLMNAKDM4EUSP2 | |
| SCHEMBL7746677 | 0.68 | ALDH1A1 (0.71) | ALDH1A1TSHRLMNAKDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472578-A | Benzo[a]phenazine antimicrobials | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1984-09-18 | — | — | US | disclosed |