Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 14/20 | 0.60 |
| ▸ | PDE7B | Q9NP56 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TTR | P02766 | 1/20 | 0.54 |
| ▸ | ALB | P02768 | 1/20 | 0.54 |
| ▸ | THRB | P10828 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.52 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6569987 | 0.82 | MAPT (0.55) | PDE7APDE7BMEN1KMT2ATDP1 | |
| SCHEMBL11182919 | 0.78 | PDE7A (0.56) | PDE7APDE7BMEN1KMT2ATDP1 | |
| SCHEMBL11411010 | 0.76 | PDE7A (0.49) | PDE7APDE7BMEN1KMT2ATTR | |
| SCHEMBL28405 | 0.75 | PDE7A (0.77) | PDE7APDE7BKMT2ATDP1GSTP1 | |
| SCHEMBL2968510 | 0.75 | PDE7A (0.68) | PDE7APDE7BMEN1KMT2ATDP1 | |
| SCHEMBL8884363 | 0.75 | PDE7A (1.00) | PDE7APDE7BMEN1KMT2ATDP1 | |
| SCHEMBL11422901 | 0.75 | PDE7A (0.63) | PDE7APDE7BMEN1KMT2AMAPT | |
| SCHEMBL11248729 | 0.75 | PDE7A (0.58) | PDE7APDE7BMEN1KMT2AGSTP1 | |
| SCHEMBL11551963 | 0.74 | TDP1 (0.59) | PDE7AMEN1KMT2ATTRALB | |
| SCHEMBL1713219 | 0.73 | PDE7A (0.65) | PDE7APDE7BMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE31717-E | 2-Chloro-3-(phenoxy or phenylthio)-6-nitro-anilines | CELAMERCK GMBH & CO. KG (DE) | 1984-10-30 | — | — | US | disclosed |
| US-4394159-A | HERBICIDES | CELAMERCK GMBH & CO. KG (DE) | 1983-07-19 | — | — | US | disclosed |
| EP-0007482-A1 | 2-Chloro-6-nitroanilines, process for their preparation, their use, herbicidal compositions | CELAMERCK GmbH & Co. KG (DE) | 1980-02-06 | — | — | EP | disclosed |