Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.55 |
| ▸ | PDE7A | Q13946 | 7/20 | 0.52 |
| ▸ | PDE7B | Q9NP56 | 2/20 | 0.52 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.52 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.44 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.44 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11070941 | 0.82 | PDE7A (0.60) | MAPTPDE7APDE7BGSTP1GSTM2 | |
| SCHEMBL810289 | 0.75 | PDE7A (0.68) | MAPTPDE7APDE7BGSTP1GSTM2 | |
| SCHEMBL2968510 | 0.75 | PDE7A (0.68) | MAPTPDE7APDE7BGSTP1GSTM2 | |
| SCHEMBL11495179 | 0.75 | PDE7A (0.51) | MAPTPDE7APDE7BGSTP1GSTM2 | |
| SCHEMBL30338244 | 0.73 | PDE7A (0.65) | MAPTPDE7APDE7BGSTP1GSTM2 | |
| SCHEMBL1713219 | 0.73 | PDE7A (0.65) | MAPTPDE7APDE7BGSTP1GSTM2 | |
| Acetic Acid SCHEMBL8213274 | 0.73 | MAPT (0.67) | MAPTPDE7APDE7BGSTP1GSTM2 | |
| SCHEMBL15155301 | 0.73 | PDE7A (0.60) | MAPTPDE7APDE7BGSTP1GSTM2 | |
| SCHEMBL4707544 | 0.72 | PDE7A (0.48) | MAPTPDE7APDE7BGSTP1GSTM2 | |
| SCHEMBL9808890 | 0.72 | PDE7A (0.49) | MAPTPDE7APDE7BGSTP1GSTM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091935-B1 | METHOD FOR PREPARING 2-NITRO-5-(PHENYLTHIO)-ANILINES | BAYER CHEMICALS AG (DE) | 2004-04-21 | — | — | EP | disclosed |
| US-6552230-B1 | Amination of a 2,4-dichloronitrobenzene with ammonia forming 5-chloro-2-nitroaniline which is reacted with a thiophenol; one pot process | BAYER AKTIENGESELLSCHAFT (DE) | 2003-04-22 | — | — | US | disclosed |
| EP-1091935-A2 | METHOD FOR PREPARING 2-NITRO-5-(PHENYLTHIO)-ANILINES | Bayer Aktiengesellschaft (DE) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001669-A2 | METHOD FOR PREPARING 2-NITRO-5-(PHENYLTHIO)-ANILINES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-01-13 | — | — | WO | disclosed |
| EP-0061110-B1 | NITRO-ANILINES | CELAMERCK GmbH & Co. KG (DE) | 1984-08-08 | — | — | EP | disclosed |
| EP-0061110-A1 | Nitro-anilines | CELAMERCK GmbH & Co. KG (DE) | 1982-09-29 | — | — | EP | disclosed |