Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.47 |
| ▸ | PPARG | P37231 | 7/20 | 0.47 |
| ▸ | PPARD | Q03181 | 7/20 | 0.47 |
| ▸ | PPARA | Q07869 | 7/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TLR2 | O60603 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | FABP4 | P15090 | 2/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3124230 | 0.84 | FFAR1 (0.42) | FFAR4FFAR1GPR84PPARD | |
| SCHEMBL10627704 | 0.80 | CA2 (0.36) | TSHRALDH1A1 | |
| SCHEMBL3315104 | 0.79 | GPR84 (0.42) | FFAR4FFAR1GPR84PPARD | |
| SCHEMBL18946295 | 0.77 | FFAR4 (0.65) | FFAR4FFAR1AKR1B1GPR84PPARG | |
| SCHEMBL18937989 | 0.77 | FFAR4 (0.65) | FFAR4FFAR1AKR1B1GPR84PPARG | |
| SCHEMBL1960267 | 0.77 | GPR84 (0.53) | FFAR4FFAR1GPR84PPARD | |
| SCHEMBL1960275 | 0.77 | GPR84 (0.53) | FFAR4FFAR1GPR84PPARD | |
| SCHEMBL1890854 | 0.77 | GPR84 (0.53) | FFAR4FFAR1GPR84PPARD | |
| SCHEMBL8629737 | 0.77 | GPR84 (0.53) | FFAR4FFAR1GPR84PPARD | |
| SCHEMBL1958214 | 0.77 | GPR84 (0.53) | FFAR4FFAR1GPR84PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4470929-A | Condensation of substituted phenylacetonitriles with dicarboxylic anhydrides | UNION CARBIDE CORPORATION (US) | 1984-09-11 | — | — | US | disclosed |
| US-4469642-A | Condensation of ring-substituted phenylacetonitriles with mono-esters of dicarboxylic acids | UNION CARBIDE CORPORATION (US) | 1984-09-04 | — | — | US | disclosed |