Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.33 |
| ▸ | CHRNG | P07510 | 1/20 | 0.33 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | CHRND | Q07001 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Morpholine SCHEMBL11069855 | 0.87 | DRD2 (0.39) | DRD2SLC6A4SLC6A3SLC6A2CHRNA1 | |
| Morpholine SCHEMBL11096912 | 0.84 | DRD2 (0.33) | DRD2SLC6A4SLC6A3SLC6A2CHRNA1 | |
| Morpholine SCHEMBL11076338 | 0.77 | SLC6A4 (0.34) | DRD2SLC6A4SLC6A3SLC6A2 | |
| Morpholine SCHEMBL11079137 | 0.77 | PSEN1 (0.32) | — | |
| Morpholine SCHEMBL11070705 | 0.77 | SLC6A4 (0.44) | DRD2SLC6A4SLC6A3SLC6A2 | |
| Morpholine SCHEMBL11069890 | 0.76 | — | — | |
| Morpholine SCHEMBL11075735 | 0.70 | SLC6A4 (0.40) | DRD2SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL11078172 | 0.68 | MAOA (0.33) | SLC6A4SLC6A3SLC6A2CHRNA1CHRNG | |
| SCHEMBL11076077 | 0.67 | SLC6A4 (0.34) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL22470125 | 0.65 | DRD2 (0.39) | DRD2SLC6A4SLC6A3SLC6A2CHRNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |