Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.33 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.33 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.33 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.32 |
| ▸ | CCR2 | P41597 | 2/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
| ▸ | F12 | P00748 | 1/20 | 0.30 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.30 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.30 |
| ▸ | F7 | P08709 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11464204 | 0.80 | TP53 (0.41) | ARKMT2A | |
| SCHEMBL11038098 | 0.79 | AR (0.52) | ARALDH1A1AADATCCR2CCR1 | |
| SCHEMBL11037709 | 0.79 | PPOX (0.53) | ALDH1A1HTR2CKMT2AGAA | |
| SCHEMBL11464105 | 0.78 | AR (0.33) | ARGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL11464099 | 0.77 | ALDH1A1 (0.39) | ARALDH1A1AADATCCR2CCR1 | |
| SCHEMBL11042402 | 0.76 | PPOX (0.45) | GAA | |
| SCHEMBL11464097 | 0.74 | MEN1 (0.45) | ARALDH1A1KMT2AGAA | |
| SCHEMBL11480931 | 0.73 | PPOX (0.40) | ALDH1A1HTR2CKMT2AGAA | |
| SCHEMBL11464675 | 0.70 | PPOX (0.40) | ALDH1A1KMT2AGAA | |
| SCHEMBL11479619 | 0.70 | KMT2A (0.46) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4437877-A | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-03-20 | — | — | US | disclosed |
| EP-0070389-A2 | 2-(2-Fluoro-4-halo-5-substituted phenyl) hydantoins, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-01-26 | — | — | EP | disclosed |
| US-4220465-A | PREEMERGENCE OR POSTEMERGENCE HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1980-09-02 | — | — | US | disclosed |
| US-4179276-A | HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-12-18 | — | — | US | disclosed |