SCHEMBL11071273

SCHEMBL11071273

C=Cn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCN(C)CC3)cc21

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.70
DRD3 P35462 1/20 0.70
MEN1 O00255 4/20 0.66
KMT2A Q03164 4/20 0.66
LMNA P02545 4/20 0.66
KDM4E B2RXH2 9/20 0.64
HPGD P15428 4/20 0.64
NPC1 O15118 1/20 0.64
HSD17B10 Q99714 4/20 0.55
GAA P10253 1/20 0.55
RAD52 P43351 1/20 0.55
BRD4 O60885 1/20 0.54
TSHR P16473 1/20 0.54
HTT P42858 1/20 0.54
CYP2J2 P51589 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
MAPT P10636 1/20 0.54
CYP1A2 P05177 1/20 0.52
TOP2A P11388 1/20 0.52
CYP2C9 P11712 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11023748 0.99 ALDH1A1 (0.69) ALDH1A1DRD3MEN1KMT2ALMNA
SCHEMBL5960539 0.88 ALDH1A1 (0.69) ALDH1A1DRD3MEN1KMT2ALMNA
SCHEMBL5960540 0.88 ALDH1A1 (0.69) ALDH1A1DRD3MEN1KMT2ALMNA
SCHEMBL11389845 0.87 MEN1 (0.54) ALDH1A1DRD3MEN1KMT2ALMNA
SCHEMBL11067348 0.87 ALDH1A1 (0.69) ALDH1A1DRD3MEN1KMT2ALMNA
SCHEMBL11394177 0.86 ALDH1A1 (0.76) ALDH1A1DRD3MEN1KMT2ALMNA
Hydrochloric Acid SCHEMBL11024974 0.86 ALDH1A1 (0.67) ALDH1A1DRD3MEN1KMT2ALMNA
SCHEMBL11064244 0.86 KDM4E (0.60) ALDH1A1DRD3MEN1KMT2ALMNA
SCHEMBL11390473 0.85 ALDH1A1 (0.77) ALDH1A1DRD3MEN1KMT2ALMNA
SCHEMBL10923356 0.84 ALDH1A1 (0.72) ALDH1A1DRD3MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4292317-A BACTERICIDES FOR GRAM NEGATIVE AND -POSITIVE BACTERIA; ANIMAL GROWTH REGULATORS LABORATORIE ROGER BELLON (FR) 1981-09-29 US claimed
US-4472579-A REACTING A PIPERAZINE WITH A CHLORO QUINOLINECARBOXYLIC ACID ESTER, HYDROLYSIS KYORIN SEIYAKU KABUSHIKI KAISHA (JP) 1984-09-18 US disclosed
US-4292317-A BACTERICIDES FOR GRAM NEGATIVE AND -POSITIVE BACTERIA; ANIMAL GROWTH REGULATORS LABORATORIE ROGER BELLON (FR) 1981-09-29 US disclosed