Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | RAD52 | P43351 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11070919 | 0.89 | ALDH1A1 (0.59) | KDM4EALDH1A1HPGDHSD17B10DRD3 | |
| SCHEMBL11067262 | 0.86 | KDM4E (0.80) | KDM4EALDH1A1HPGDHSD17B10DRD3 | |
| SCHEMBL11071273 | 0.86 | ALDH1A1 (0.70) | KDM4EALDH1A1HPGDHSD17B10DRD3 | |
| SCHEMBL9431942 | 0.85 | KDM4E (0.59) | KDM4EALDH1A1HPGDHSD17B10DRD3 | |
| Hydrochloric Acid SCHEMBL11023748 | 0.85 | ALDH1A1 (0.69) | KDM4EALDH1A1HPGDHSD17B10DRD3 | |
| SCHEMBL10920758 | 0.84 | KDM4E (0.60) | KDM4EALDH1A1HPGDHSD17B10DRD3 | |
| SCHEMBL10471206 | 0.84 | KMT2A (0.73) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL29576777 | 0.83 | ALDH1A1 (0.66) | KDM4EALDH1A1HPGDHSD17B10DRD3 | |
| SCHEMBL9638922 | 0.83 | ALDH1A1 (0.66) | KDM4EALDH1A1HPGDHSD17B10DRD3 | |
| SCHEMBL11406037 | 0.83 | KDM4E (0.67) | KDM4EALDH1A1HPGDHSD17B10DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472579-A | REACTING A PIPERAZINE WITH A CHLORO QUINOLINECARBOXYLIC ACID ESTER, HYDROLYSIS | KYORIN SEIYAKU KABUSHIKI KAISHA (JP) | 1984-09-18 | — | — | US | disclosed |