Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | CPA3 | P15088 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071293 | 1.00 | MAPT (0.51) | MAPTRXFP1SMN1; SMN2HDAC3MAPK1 | |
| SCHEMBL11071468 | 0.99 | MAPT (0.54) | MAPTRXFP1SMN1; SMN2HDAC3MAPK1 | |
| SCHEMBL11071463 | 0.99 | MAPT (0.54) | MAPTRXFP1SMN1; SMN2HDAC3MAPK1 | |
| SCHEMBL10816014 | 0.96 | SMN1; SMN2 (0.51) | MAPTRXFP1SMN1; SMN2HDAC3MAPK1 | |
| SCHEMBL10816013 | 0.96 | SMN1; SMN2 (0.51) | MAPTRXFP1SMN1; SMN2HDAC3MAPK1 | |
| SCHEMBL10815670 | 0.90 | CPA3 (0.51) | MAPTSMN1; SMN2HDAC3MAPK1ADRA1A | |
| SCHEMBL10815672 | 0.90 | CPA3 (0.51) | MAPTSMN1; SMN2HDAC3MAPK1ADRA1A | |
| SCHEMBL6778466 | 0.88 | MEN1 (0.53) | MAPTSMN1; SMN2ALOX5MEN1NPC1 | |
| SCHEMBL10815058 | 0.87 | MAPT (0.56) | MAPTRXFP1SMN1; SMN2HDAC3MAPK1 | |
| SCHEMBL10816854 | 0.86 | MAPT (0.58) | MAPTRXFP1SMN1; SMN2HDAC3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0105919-A1 | 1-CARBOXYALKANOYLPERHYDROINDOLE-2-CARBOXYLIC ACIDS AND DERIVATIVES. | CIBA GEIGY AG (CH) | 1984-04-25 | — | — | EP | disclosed |
| WO-1983003828-A1 | 1-CARBOXYALKANOYLPERHYDROINDOLE-2-CARBOXYLIC ACIDS AND DERIVATIVES | CIBA-GEIGY AG (CH) | 1983-11-10 | — | — | WO | disclosed |