Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.38 |
| ▸ | PDE4A | P27815 | 2/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11081203 | 0.95 | CNR1 (0.51) | CNR1CNR2PDE4BPDE4APDE4C | |
| SCHEMBL10973972 | 0.92 | CNR1 (0.57) | CNR1CNR2PDE4BPDE4APDE4C | |
| SCHEMBL11073415 | 0.87 | CNR1 (0.48) | CNR1CNR2PDE4BPDE4APDE4C | |
| SCHEMBL844232 | 0.85 | CNR1 (0.69) | CNR1CNR2TP53 | |
| SCHEMBL11071494 | 0.85 | CNR1 (0.48) | CNR1CNR2PDE4BPDE4APDE4C | |
| SCHEMBL11075597 | 0.84 | CNR1 (0.56) | CNR1CNR2PDE4BPDE4APDE4C | |
| SCHEMBL10975710 | 0.84 | CNR1 (0.54) | CNR1CNR2PDE4BPDE4APDE4C | |
| SCHEMBL11081687 | 0.83 | CNR1 (0.59) | CNR1CNR2PDE4BPDE4APDE4C | |
| SCHEMBL11079598 | 0.82 | CNR1 (0.56) | CNR1CNR2ALDH1A1LMNATHRB | |
| SCHEMBL11071848 | 0.82 | CNR1 (0.57) | CNR1CNR2ALDH1A1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4451467-A | HYPOTENSIVE AGENTS | Ishikawa, Masayuki (JP) | 1984-05-29 | — | — | US | disclosed |
| EP-0056637-A1 | 4(3H)-quinazolinone derivatives, process for production thereof and pharmaceutical compositions comprising said compounds | Ishikawa, Masayuki (JP) | 1982-07-28 | — | — | EP | disclosed |