SCHEMBL11071801

SCHEMBL11071801

CCC(C)(Br)C(=O)OC(C)(C)C

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.43
CA12 O43570 1/20 0.32
CA1 P00915 1/20 0.32
CA7 P43166 1/20 0.32
CA14 Q9ULX7 1/20 0.32
APLNR P35414 1/20 0.32
ELANE P08246 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
ALDH1A1 P00352 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6774761 0.81 DGAT1 (0.43) DGAT1CA12CA1CA7CA14
SCHEMBL3358751 0.78
SCHEMBL8037991 0.78
SCHEMBL1854077 0.78
SCHEMBL675195 0.76 CYP4F2 (0.42) ALDH1A1KMT2A
SCHEMBL2703489 0.76
SCHEMBL10032096 0.76 DGAT1 (0.35) DGAT1
SCHEMBL47394 0.75 DGAT1 (0.46) DGAT1CA12CA1CA7CA14
SCHEMBL15082441 0.75 DGAT1 (0.46) DGAT1CA12CA1CA7CA14
SCHEMBL28004334 0.75 DGAT1 (0.46) DGAT1CA12CA1CA7CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170361281-A1 FILTRATION MEMBRANES WITH FUNCTIONALIZED STAR POLYMERS INTERNATIONAL BUSINESS MACHINES CORPORATION 2017-12-21 US disclosed
US-9782727-B2 Filtration membranes with functionalized star polymers INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2017-10-10 US disclosed
US-20160008769-A1 FILTRATION MEMBRANES WITH FUNCTIONALIZED STAR POLYMERS INTERNATIONAL BUSINESS MACHINES CORPORATION 2016-01-14 US disclosed
US-4474779-A ANTIBIOTICS, BACTERICIDES YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) 1984-10-02 US disclosed
EP-0118838-A2 New cephem compounds processes for preparation thereof and pharmaceutical compositions containing them FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-09-19 EP disclosed