SCHEMBL11071872

SCHEMBL11071872

Nc1ncnc(S(=O)(=O)O)n1

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.35
HSP90AA1 P07900 1/20 0.33
BCL6 P41182 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
NT5E P21589 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2C19 P33261 1/20 0.31
HSD17B10 Q99714 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
SLC6A2 P23975 1/20 0.31
PDE4A P27815 1/20 0.31
KDR P35968 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10780407 0.84 KDM4E (0.32) KDM4ETSHRCYP1A2CYP2C19HSD17B10
SCHEMBL27656919 0.74
SCHEMBL27976239 0.74 TSHR (0.33) KDM4EALDH1A1TSHRNT5ECYP1A2
SCHEMBL9395961 0.74 CYP1A2 (0.36) KDM4EALDH1A1TSHRNT5ECYP1A2
SCHEMBL27764568 0.72
SCHEMBL29065907 0.72 TSHR (0.59) KDM4EBCL6ALDH1A1TSHRNT5E
Water SCHEMBL6716218 0.71
SCHEMBL11407198 0.69 LMNA (0.33) CYP1A2SMN1; SMN2
SCHEMBL8020815 0.69
Octane SCHEMBL28223647 0.69 ALDH1A1 (0.38) KDM4EALDH1A1TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1155582-C Process for the preparation of 2-amino-4-chloro-1, 3, 5-triazines �Ϻ���ͨ��ѧ 2004-06-30 CN claimed
CN-1306518-A Process for the preparation of 2-amino-4-chloro-1, 3, 5-triazines AVENTIES CROPS SCIENCES GMBH (DE) 2001-08-01 CN claimed
JP-57133192-A None JP disclosed
US-12036208-B2 Methods for treating neurodegenerative disorders ALZHEON, INC. (US) 2024-07-16 US disclosed
US-12036208-B2 Methods for treating neurodegenerative disorders ALZHEON, INC. (US) 2024-07-16 US disclosed
US-11077095-B2 Methods for treating neurodegenerative disorders ALZHEON, INC. (US) 2021-08-03 US disclosed
CN-1155582-C Process for the preparation of 2-amino-4-chloro-1, 3, 5-triazines �Ϻ���ͨ��ѧ 2004-06-30 CN disclosed
CN-1137108-C Fluorinated triazine monomers 2004-02-04 CN disclosed
CN-1306518-A Process for the preparation of 2-amino-4-chloro-1, 3, 5-triazines AVENTIES CROPS SCIENCES GMBH (DE) 2001-08-01 CN disclosed
CN-1271350-A Fluorinated triazine monomers SECR DEFENCE (GB) 2000-10-25 CN disclosed
US-4470828-A INCLUDING A MODIFIED POLYETHER AND A SULFONATED ANIONIC SURFACTANT; FLUID FLOW; ANTISTATIC AGENTS KAO CORPORATION (JP) 1984-09-11 US disclosed
JP-S57133192-A DISPERSANT FOR POWDERY COAL-WATER SLURRY KAO CORP 1982-08-17 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11077095-B2 Methods for treating neurodegenerative disorders NLN, CLN6, SNCA KDM4E 3838/4885HSP90AA1 305/4885BCL6 1887/4885
US-12036208-B2 Methods for treating neurodegenerative disorders NLN, CLN6, SNCA KDM4E 3838/4885HSP90AA1 305/4885BCL6 1887/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.