Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11072034 | 0.95 | ALDH1A1 (0.37) | MAPTHTTTP53AKR1B1ALDH1A1 | |
| SCHEMBL11063934 | 0.88 | MAPT (0.41) | MAPTHTTTP53AKR1B1ALDH1A1 | |
| SCHEMBL11063854 | 0.74 | CA1 (0.58) | MAPTHTTALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL11075437 | 0.72 | MAPT (0.42) | MAPTTP53SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10727373 | 0.71 | HTT (0.47) | MAPTHTTALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL11069902 | 0.70 | PLK1 (0.41) | CA1CA2 | |
| SCHEMBL10727939 | 0.70 | CA1 (0.49) | MAPTHTTGAAHDAC3HDAC1 | |
| SCHEMBL6674869 | 0.66 | TDP1 (0.47) | MAPTHTTALDH1A1GAA | |
| SCHEMBL3477681 | 0.66 | MAPT (0.65) | MAPTHTTTP53ALDH1A1GAA | |
| SCHEMBL8781083 | 0.65 | ALDH1A1 (0.51) | MAPTTP53ALDH1A1GAACA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4480105-A | PHOTOCROSSLINKING POLYMERS | CIBA-GEIGY CORPORATION (US) | 1984-10-30 | — | — | US | disclosed |
| US-4363917-A | SENSITIZERS FOR PHOTOCROSSLINKABLE POLYMERS; PHOTOPOLYMERIZATION INITIATORS | CIBA-GEIGY CORPORATION (US) | 1982-12-14 | — | — | US | disclosed |