Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | RORC | P51449 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | USP7 | Q93009 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11063934 | 0.76 | MAPT (0.41) | MAPTLMNATDP1MEN1KMT2A | |
| SCHEMBL11074249 | 0.72 | PDE7A (0.50) | MAPTLMNATDP1MEN1KMT2A | |
| SCHEMBL11071900 | 0.72 | MAPT (0.38) | MAPTLMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11063854 | 0.72 | CA1 (0.58) | MAPTLMNARECQLTDP1MEN1 | |
| SCHEMBL4361418 | 0.71 | RORC (0.65) | MAPTLMNAMEN1KMT2ARORC | |
| SCHEMBL11072034 | 0.70 | ALDH1A1 (0.37) | MAPTLMNATP53 | |
| SCHEMBL23709706 | 0.69 | PLK1 (0.45) | MAPTLMNAKMT2ASMN1; SMN2SLC6A2 | |
| SCHEMBL7608814 | 0.68 | PDE7A (0.71) | MAPTLMNARECQLTDP1KMT2A | |
| SCHEMBL28549966 | 0.67 | POLB (0.80) | MAPTLMNAMEN1KMT2AMAPK1 | |
| SCHEMBL10925413 | 0.67 | MAPT (0.66) | MAPTLMNARECQLTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4480105-A | PHOTOCROSSLINKING POLYMERS | CIBA-GEIGY CORPORATION (US) | 1984-10-30 | — | — | US | disclosed |
| US-4363917-A | SENSITIZERS FOR PHOTOCROSSLINKABLE POLYMERS; PHOTOPOLYMERIZATION INITIATORS | CIBA-GEIGY CORPORATION (US) | 1982-12-14 | — | — | US | disclosed |