Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.34 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.34 |
| ▸ | HTR1D | P28221 | 2/20 | 0.34 |
| ▸ | HTR1B | P28222 | 2/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11071980 | 1.00 | SLC6A4 (0.37) | SLC6A4SLC6A2SLC6A3DRD2HTR2C | |
| SCHEMBL27397494 | 0.87 | HTR1D (0.44) | SLC6A4SLC6A2SLC6A3DRD2HTR1D | |
| SCHEMBL11835299 | 0.86 | SLC6A4 (0.38) | SLC6A4SLC6A2SLC6A3DRD2CYSLTR2 | |
| SCHEMBL8207133 | 0.86 | SLC6A4 (0.36) | SLC6A4SLC6A2SLC6A3DRD2HTR2C | |
| Hydrochloric Acid SCHEMBL7994679 | 0.85 | HTR1D (0.43) | SLC6A4SLC6A2SLC6A3DRD2HTR2C | |
| SCHEMBL4825129 | 0.85 | HTR1D (0.43) | SLC6A4SLC6A2SLC6A3DRD2HTR1D | |
| SCHEMBL11474957 | 0.84 | CYP2C9 (0.41) | SLC6A4SLC6A2SLC6A3DRD2MEN1 | |
| SCHEMBL4797383 | 0.79 | MAPT (0.38) | DRD2CYSLTR2CYSLTR1MEN1KMT2A | |
| SCHEMBL4797393 | 0.79 | MAPT (0.38) | DRD2CYSLTR2CYSLTR1MEN1KMT2A | |
| SCHEMBL8433540 | 0.78 | CYP2C9 (0.42) | SLC6A4SLC6A2SLC6A3HCRTR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4477369-A | New high temperature liquid-crystalline substances consisting of 4 or 5 six-member-rings and liquid-crystalline compositions containing same | CHISSO CORPORATION (JP) | 1984-10-16 | — | — | US | disclosed |
| EP-0084974-A1 | Carbocyclic compounds with liquid-crystal properties | Chisso Corporation (JP) | 1983-08-03 | — | — | EP | disclosed |