SCHEMBL4825129

SCHEMBL4825129

CCCc1ccccc1C1CCCCC1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HTR1D P28221 2/20 0.43
HTR1B P28222 2/20 0.43
EPHX2 P34913 1/20 0.43
PTGDR2 Q9Y5Y4 1/20 0.41
NAAA Q02083 1/20 0.40
PTGS2 P35354 1/20 0.40
CTSK P43235 3/20 0.39
CTSS P25774 2/20 0.39
SLC6A4 P31645 2/20 0.37
SLC6A2 P23975 1/20 0.37
SLC6A3 Q01959 1/20 0.37
DRD2 P14416 3/20 0.36
DRD1 P21728 1/20 0.36
DRD4 P21917 1/20 0.36
DRD5 P21918 1/20 0.36
DRD3 P35462 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27397494 0.98 HTR1D (0.44) HTR1DHTR1BEPHX2PTGDR2NAAA
Hydrochloric Acid SCHEMBL7994679 0.96 HTR1D (0.43) HTR1DHTR1BEPHX2PTGDR2NAAA
SCHEMBL15568277 0.89 HTR1D (0.43) HTR1DHTR1BPTGDR2NAAAPTGS2
SCHEMBL9845530 0.89 HTR1D (0.43) HTR1DHTR1BPTGDR2NAAAPTGS2
SCHEMBL27472566 0.88 CYSLTR2 (0.47) HTR1DHTR1BPTGDR2NAAAPTGS2
SCHEMBL28076276 0.86 CYSLTR2 (0.49) HTR1DHTR1BSLC6A4SLC6A2DRD2
SCHEMBL11278522 0.86 CYSLTR2 (0.49) HTR1DHTR1BSLC6A4SLC6A2DRD2
SCHEMBL27472563 0.86 CYSLTR2 (0.48) HTR1DHTR1BPTGS2SLC6A4SLC6A2
SCHEMBL11071980 0.85 SLC6A4 (0.37) HTR1DHTR1BSLC6A4SLC6A2SLC6A3
SCHEMBL11071982 0.85 SLC6A4 (0.37) HTR1DHTR1BSLC6A4SLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110041275-B 4-propylcyclohexylbenzene derivative containing 1,2, 3-triazole five-membered ring and preparation method thereof 四川师范大学 2022-07-01 CN claimed
WO-2023245790-A1 METHOD FOR PREPARING CYCLOALKANE FROM CYCLIC ALCOHOL IN ONE STEP BY MEANS OF MOLECULAR SIEVE 中节能万润股份有限公司 2023-12-28 WO disclosed
CN-114890857-B Method for preparing cycloalkane from cyclic alcohol in one step through molecular sieve 中节能万润股份有限公司 2023-04-07 CN disclosed
CN-114890857-A Method for preparing cycloalkane from cyclic alcohol in one step through molecular sieve 中节能万润股份有限公司 2022-08-12 CN disclosed
CN-111072446-A Preparation method of alkyl cyclohexyl bromobenzene 烟台坤益液晶显示材料有限公司 2020-04-28 CN disclosed
CN-106967443-A The preparation method of alkyl cyclohexyl biphenyl nitrile liquid-crystal compounds 烟台德润液晶材料有限公司 2017-07-21 CN disclosed
EP-1731587-B1 Process for the preparation of tolanes MERCK PATENT GMBH (DE) 2013-01-23 EP disclosed
US-7335405-B2 Nematic liquid crystal mixtures for use in bistable display devices NEMOPTIC (FR) 2008-02-26 US disclosed
EP-1731587-A1 Tolanes, process for their preparation and use thereof MERCK PATENT GmbH (DE) 2006-12-13 EP disclosed
US-20060249708-A1 Nematic liquid crystal mixtures for use in bistable display devices CDC PROPRIETE INTELLECTUELLE (FR) 2006-11-09 US disclosed
US-7115307-B2 Nematic liquid crystal mixtures for bistable display device NEMOPTIC (FR) 2006-10-03 US disclosed
EP-1329259-A2 Continuous method for hydrolysis of a solvent containing organic compound MERCK PATENT GmbH (DE) 2003-07-23 EP disclosed
US-4371726-A Composition suitable for mechanical power transmission and process for operating traction drives NIPPON STEEL CHEMICAL CO., LTD. (JP) 1983-02-01 US disclosed