Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 2/20 | 0.44 |
| ▸ | HTR1B | P28222 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 3/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7994679 | 0.98 | HTR1D (0.43) | HTR1DHTR1BEPHX2SLC6A4SLC6A2 | |
| SCHEMBL4825129 | 0.98 | HTR1D (0.43) | HTR1DHTR1BEPHX2SLC6A4SLC6A2 | |
| SCHEMBL27472563 | 0.87 | CYSLTR2 (0.48) | HTR1DHTR1BSLC6A4SLC6A2DRD2 | |
| SCHEMBL15568277 | 0.87 | HTR1D (0.43) | HTR1DHTR1BPTGDR2NAAAPTGS2 | |
| SCHEMBL9845530 | 0.87 | HTR1D (0.43) | HTR1DHTR1BPTGDR2NAAAPTGS2 | |
| SCHEMBL11071980 | 0.87 | SLC6A4 (0.37) | HTR1DHTR1BSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL11071982 | 0.87 | SLC6A4 (0.37) | HTR1DHTR1BSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL27472566 | 0.86 | CYSLTR2 (0.47) | HTR1DHTR1BPTGDR2NAAAPTGS2 | |
| SCHEMBL28076276 | 0.84 | CYSLTR2 (0.49) | HTR1DHTR1BSLC6A4SLC6A2DRD2 | |
| SCHEMBL11278522 | 0.84 | CYSLTR2 (0.49) | HTR1DHTR1BSLC6A4SLC6A2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1092647-C | New antiviral substituted pyrimidinedione homocarbocyclic nucleoside derivatives and methods for preparation thereof and compositions containing the same as active ingredients | SAMJIN PHARM CO LTD (KR) | 2002-10-16 | — | — | CN | disclosed |
| CN-1182420-A | Novel antiviral substituted pyrimidinedione homocarbocyclic nucleoside derivatives, process for preparing the same and composition containing the same as active ingredient | SAMJIN PHARM CO LTD (KR) | 1998-05-20 | — | — | CN | disclosed |