SCHEMBL11072067

SCHEMBL11072067

CCCCOC(=O)C(N)CCCO

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NOD1 Q9Y239 4/20 0.50
ALDH1A1 P00352 1/20 0.45
ATM Q13315 1/20 0.42
ACHE P22303 6/20 0.41
TSHR P16473 3/20 0.40
HPGD P15428 1/20 0.40
DPP7 Q9UHL4 1/20 0.40
SLC15A1 P46059 1/20 0.40
HCAR2 Q8TDS4 1/20 0.38
LMNA P02545 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
PDE4D Q08499 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28674497 0.93 NOD1 (0.47) NOD1ALDH1A1ATMACHEDPP7
SCHEMBL29119304 0.91 NOD1 (0.49) NOD1ALDH1A1ACHEDPP7SLC15A1
SCHEMBL29119022 0.91 NOD1 (0.49) NOD1ALDH1A1ACHEDPP7
SCHEMBL3452377 0.91 ALDH1A1 (0.47) NOD1ALDH1A1ATMACHETSHR
SCHEMBL27876244 0.91 ALDH1A1 (0.47) NOD1ALDH1A1ATMACHETSHR
SCHEMBL1097461 0.90 NOD1 (0.50) NOD1ALDH1A1ATMTSHRHPGD
SCHEMBL4957809 0.90 NOD1 (0.50) NOD1ALDH1A1ATMTSHRHPGD
SCHEMBL28593296 0.89 NOD1 (0.51) NOD1ACHEDPP7
SCHEMBL29119093 0.89 NOD1 (0.51) NOD1ACHEDPP7
SCHEMBL29073359 0.89 NOD1 (0.51) NOD1ACHEDPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0046711-B1 FLUORINATED AMINO-BUTYRIC ACID AND DIAMINOBUTANE DERIVATIVES MERRELL TORAUDE ET COMPAGNIE (FR) 1984-09-05 EP disclosed