Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 6/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11079377 | 0.90 | OPRL1 (0.45) | OPRL1OPRM1KDM2B | |
| SCHEMBL11070148 | 0.86 | OPRL1 (0.49) | OPRL1MMP1MMP2MMP9MMP13 | |
| SCHEMBL11069281 | 0.86 | OPRL1 (0.46) | OPRL1OPRM1OPRK1 | |
| SCHEMBL11073750 | 0.80 | OPRL1 (0.50) | OPRL1MMP1MMP2MMP9MMP13 | |
| SCHEMBL11069606 | 0.78 | OPRL1 (0.40) | OPRL1OPRM1OPRK1 | |
| SCHEMBL11071725 | 0.78 | OPRL1 (0.37) | OPRL1OPRM1KDM2BOPRK1 | |
| SCHEMBL11071160 | 0.77 | SLC6A3 (0.38) | OPRL1KMT2AOPRM1OPRK1 | |
| SCHEMBL11070189 | 0.77 | OPRL1 (0.43) | OPRL1KMT2AOPRM1KDM2BOPRK1 | |
| SCHEMBL11078360 | 0.77 | OPRL1 (0.37) | OPRL1KMT2AOPRM1OPRK1 | |
| SCHEMBL11074165 | 0.77 | OPRL1 (0.44) | OPRL1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |