Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 15/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 11/20 | 0.45 |
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11072181 | 0.90 | OPRL1 (0.43) | OPRL1OPRM1KDM2B | |
| SCHEMBL11069281 | 0.87 | OPRL1 (0.46) | OPRL1OPRM1 | |
| SCHEMBL11069516 | 0.86 | OPRL1 (0.50) | OPRL1OPRM1 | |
| SCHEMBL11071725 | 0.83 | OPRL1 (0.37) | OPRL1OPRM1KDM2B | |
| SCHEMBL11069606 | 0.79 | OPRL1 (0.40) | OPRL1OPRM1 | |
| SCHEMBL11071160 | 0.78 | SLC6A3 (0.38) | OPRL1OPRM1 | |
| SCHEMBL11074165 | 0.78 | OPRL1 (0.44) | OPRL1OPRM1 | |
| SCHEMBL11078360 | 0.78 | OPRL1 (0.37) | OPRL1OPRM1 | |
| SCHEMBL11070850 | 0.77 | OPRL1 (0.53) | OPRL1OPRM1KDM2B | |
| SCHEMBL11078645 | 0.76 | SLC6A3 (0.36) | OPRL1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |