Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP5 | Q13451 | 17/20 | 0.89 |
| ▸ | FKBP4 | Q02790 | 5/20 | 0.86 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.86 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.86 |
| ▸ | HRH2 | P25021 | 1/20 | 0.86 |
| ▸ | HTR1D | P28221 | 1/20 | 0.86 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.86 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.86 |
| ▸ | FKBP2 | P26885 | 1/20 | 0.86 |
| ▸ | FKBP1B | P68106 | 1/20 | 0.86 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.86 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20777055 | 1.00 | FKBP5 (0.89) | FKBP5FKBP4FKBP1ATMEM97HRH2 | |
| SCHEMBL15791499 | 1.00 | FKBP5 (0.89) | FKBP5FKBP4FKBP1ATMEM97HRH2 | |
| SCHEMBL17231762 | 1.00 | FKBP5 (0.89) | FKBP5FKBP4FKBP1ATMEM97HRH2 | |
| SCHEMBL29353775 | 1.00 | FKBP5 (0.89) | FKBP5FKBP4FKBP1ATMEM97HRH2 | |
| SCHEMBL15927319 | 0.95 | FKBP5 (0.81) | FKBP5FKBP4FKBP1ATMEM97HRH2 | |
| SCHEMBL24262241 | 0.95 | FKBP5 (0.80) | FKBP5FKBP4FKBP1ATMEM97HRH2 | |
| SCHEMBL20777143 | 0.95 | FKBP5 (0.80) | FKBP5FKBP4FKBP1ATMEM97HRH2 | |
| SCHEMBL20777069 | 0.95 | FKBP5 (0.80) | FKBP5FKBP4FKBP1ATMEM97HRH2 | |
| SCHEMBL24390118 | 0.95 | FKBP5 (0.80) | FKBP5FKBP4FKBP1ATMEM97HRH2 | |
| SCHEMBL19719556 | 0.94 | FKBP5 (0.96) | FKBP5FKBP4FKBP1ATMEM97HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230235278-A1 | Protein Enriched Microvesicles and Methods of Making and Using the Same | TAKARA BIO USA, INC. | 2023-07-27 | — | — | US | disclosed |
| US-11643635-B2 | Protein enriched microvesicles and methods of making and using the same | TAKARA BIO USA, INC. (US) | 2023-05-09 | — | — | US | disclosed |
| US-8153785-B2 | Stabilizing ligands for regulation of protein function | Cheminpharma LLC (US) | 2012-04-10 | — | — | US | disclosed |
| US-20100267950-A1 | Novel Stabilizing Ligands For Regulation of Protein Function | Cheminpharma LLC (US) | 2010-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267950-A1 | Novel Stabilizing Ligands For Regulation of Protein Function | MRPL21, ASF1A, G3BP2 | FKBP5 1316/4885FKBP4 1370/4885FKBP1A 719/4885 |
| US-11643635-B2 | Protein enriched microvesicles and methods of making and using the same | CHMP4B, VAPB, PEBP1 | FKBP5 1675/4885FKBP4 2190/4885FKBP1A 1760/4885 |
| US-20230235278-A1 | Protein Enriched Microvesicles and Methods of Making and Using the Same | CHMP4B, VAPB, PEBP1 | FKBP5 1675/4885FKBP4 2190/4885FKBP1A 1760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.