PEBP1

Phosphatidylethanolamine-binding protein 1 · P30086 · PEBP1 on Sugi Atlas →

600 patent compounds predicted against PEBP1, 526 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
Tivozanib Tivozanib (SCHEMBL172883) 1.00 1/20
Tivozanib Tivozanib (SCHEMBL29354238) 1.00 1/20
Tivozanib Tivozanib (SCHEMBL29354604) 1.00 1/20
Tivozanib Tivozanib (SCHEMBL1869882) 0.98 1/20
Tivozanib Tivozanib (SCHEMBL30993908) 0.98 1/20
Tivozanib Tivozanib (SCHEMBL21174286) 0.97 1/20
Tivozanib Tivozanib (SCHEMBL29394095) 0.97 1/20
Tivozanib Tivozanib (SCHEMBL5209537) 0.93 1/20
Tivozanib Tivozanib (SCHEMBL5214691) 0.93 1/20
Tivozanib Tivozanib (SCHEMBL5211590) 0.90 1/20
Tivozanib Tivozanib (SCHEMBL5213723) 0.90 1/20
Tivozanib Tivozanib (SCHEMBL5545131) 0.90 1/20
SCHEMBL14409673 SCHEMBL14409673 0.89 1/20
SCHEMBL15962810 SCHEMBL15962810 0.89 1/20
Tivozanib Tivozanib (SCHEMBL27218324) 0.89 1/20
SCHEMBL15962809 SCHEMBL15962809 0.88 1/20
SCHEMBL15962834 SCHEMBL15962834 0.88 1/20
SCHEMBL31452948 SCHEMBL31452948 0.86 1/20
Tivozanib Tivozanib (SCHEMBL5214257) 0.84 1/20
SCHEMBL19645596 SCHEMBL19645596 0.84 1/20

Clinical trials — most relevant to PEBP1 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
Study of Sorafenib and Docetaxel in Metastatic Prostate Cancer PHASE2COMPLETED
NEO100 and High-Grade Meningioma PHASE2RECRUITING
Effect of Gemfibrozil on Serum Glycosylphosphatidylinositol (GPI) Phospholipase D and Triglycerides PHASE1COMPLETED
the Role of plin5 in the Development of Nonalcoholic Fatty Liver Disease. nanUNKNOWN
Development of Biomarker for Development of Non-Alcoholic Steatohepatitis (NASH) in Children nanWITHDRAWN
Neutrophils as Prognostic Factors in Granulomatosis With Polyangiitis (Formerly Named Wegener's Granulomatosis) nanCOMPLETED
Study of Blood Samples From High-Risk Postmenopausal Women Who Received Treatment on Breast Cancer Prevention Clinical Trials NSABP-P-1 or NSABP-P-2 nanUNKNOWN
Autophagy in Systemic Lupus Erythematosus nanUNKNOWN
Investigation of Secreted Phosphoproteins and PiP3 (Phosphoinositolphospat 3) in Sputum nanCOMPLETED
Young Pectus Excavatum Patients and Genetic Defects nanCOMPLETED
Choline to Improve Malnutrition and Enhance Cognition nanRECRUITING
Study of the Pathophysiological Mechanisms Involved in Bleeding Events nanCOMPLETED
Characterization of New Candidate Genes in Cases of Human Inherited Thrombocytopenia (CATCH) nanCOMPLETED
Immune Cell Response to Stimuli nanRECRUITING
PCD New Gene Discovery nanCOMPLETED
Composition & Function of Sarcoplasmic Reticulum in Persons With the Metabolic Syndrome nanCOMPLETED
Vitreous Proteomics of Patients Suffering From Pseudoexfoliation Syndrome nanACTIVE_NOT_RECRUITING
Epidemiology of Atherosclerosis nanCOMPLETED
Chest Wall Deformities in Children - Epidemiological Data nanCOMPLETED
Predictive Value of Maternal Blood Protein Signatures in Preterm Birth nanCOMPLETED
Pathogenesis of Primary Ciliary Dyskinesia (PCD) Lung Disease nanRECRUITING
Surfactant Derived Protocol in Heart Failure nanCOMPLETED
Combining Gene Variants to Improve Risk Prediction for Metabolic (Dysfunction)- Associated Fatty Liver Disease and Its Progression to Cirrhosis in Indian Individuals With Type 2 Diabetes nanCOMPLETED
Inflammatory Genomics in Human Carotid Artery Disease nanCOMPLETED
Autophagy Bladder Cancer nanUNKNOWN
Velocardiofacial (VCFS; 22q11.2; DiGeorge) Syndrome Study nanCOMPLETED
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases nanUNKNOWN
Unraveling Genetics of HypoPhosPhatasia (HPP Genetics) nanCOMPLETED
Identification of a New Blood Biomarker for the Diagnosis and Prognosis of Liposarcomas nanRECRUITING
Familial Partial Lipodystrophy Study nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a PEBP1 binder may also engage these)

ProteinNameSimilarity
Q5R4R0 1.000 Q5R4R0 →
Q3YIX4 1.000 Q3YIX4 →
Q8MK67 1.000 Q8MK67 →
P31044 1.000 P31044 →
P13696 0.998 P13696 →
P48737 0.998 P48737 →
O16264 0.993 O16264 →
P70296 0.992 P70296 →
Q656A5 0.990 Q656A5 →
Q06252 0.990 Q06252 →
P14306 0.987 P14306 →
Q93WI9 0.986 Q93WI9 →
Q41261 0.985 Q41261 →
P54186 0.985 P54186 →
Q9XFK7 0.985 Q9XFK7 →
Q9XH44 0.982 Q9XH44 →
P54188 0.981 P54188 →
Q9FIT4 0.981 Q9FIT4 →
P31729 0.980 P31729 →
A0A286R227 0.980 A0A286R227 →
P93028 0.979 P93028 →
P14882 0.979 P14882 →
Q7SIA2 0.979 Q7SIA2 →
Q38970 0.979 Q38970 →
Q9C566 0.979 Q9C566 →
P93834 0.979 P93834 →
Q21693 0.978 Q21693 →
P14946 0.978 P14946 →
O14224 0.978 O14224 →
P83753 0.978 P83753 →