Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 6/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 4/20 | 0.32 |
| ▸ | HTR7 | P34969 | 4/20 | 0.32 |
| ▸ | HTR5A | P47898 | 4/20 | 0.32 |
| ▸ | HTR1D | P28221 | 3/20 | 0.32 |
| ▸ | HRH1 | P35367 | 2/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3343457 | 0.83 | AR (0.45) | AR | |
| SCHEMBL2330720 | 0.83 | AR (0.45) | AR | |
| SCHEMBL8979369 | 0.83 | AR (0.45) | AR | |
| Hydrochloric Acid SCHEMBL10575020 | 0.82 | AR (0.44) | AR | |
| SCHEMBL10434062 | 0.81 | AR (0.43) | ARHTR2CHTR2AHTR2BPGR | |
| SCHEMBL28588500 | 0.81 | AR (0.40) | ARHTR2CHTR1AHTR7HTR5A | |
| SCHEMBL11854527 | 0.77 | HTR5A (0.43) | ARHTR2CHTR2AHTR1AHTR7 | |
| SCHEMBL10834821 | 0.74 | AR (0.43) | AR | |
| SCHEMBL2599597 | 0.73 | AR (0.42) | ARPGR | |
| SCHEMBL14567675 | 0.73 | AR (0.44) | AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0047005-B1 | BENZOXAZINE DERIVATIVES | DAIICHI SEIYAKU CO., LTD. (JP) | 1984-11-14 | — | — | EP | disclosed |
| US-4382892-A | Benzoxazine derivatives | DAIICHI SEIYAKU CO., LTD. (JP) | 1983-05-10 | — | — | US | disclosed |
| EP-0047005-A1 | Benzoxazine derivatives | DAIICHI SEIYAKU CO., LTD. (JP) | 1982-03-10 | — | — | EP | disclosed |