SCHEMBL8979369

SCHEMBL8979369

C[C@@H]1COc2c(ccc(F)c2F)N1

nearest known ligand 0.45

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
AR P10275 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2330720 1.00 AR (0.45) AR
SCHEMBL3343457 1.00 AR (0.45) AR
Hydrochloric Acid SCHEMBL10575020 0.98 AR (0.44) AR
SCHEMBL11072789 0.83 AR (0.43) AR
SCHEMBL10834821 0.83 AR (0.43) AR
SCHEMBL10434062 0.83 AR (0.43) AR
SCHEMBL2599597 0.79 AR (0.42) AR
SCHEMBL10676628 0.79 AR (0.43) AR
SCHEMBL10434361 0.77 AR (0.36) AR
SCHEMBL9601583 0.76 AR (0.35) AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0322815-B1 Propoxybenzene derivatives and process for preparing the same DAIICHI SEIYAKU CO (JP) 1996-05-15 EP disclosed
US-5312999-A Propoxybenzene derivatives and process for preparing the same DAIICHI SEIYAKU CO., LTD. (JP) 1994-05-17 US disclosed
US-5136059-A PROPOXYBENZENE DERIVATIVES AND PROCESS FOR PREPARING THE SAME DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1992-08-04 US disclosed
EP-0368410-A2 Optically active benzoxazines and bezothiazines and a process for their stereospecific preparation GIST-BROCADES N.V. (NL) 1990-05-16 EP disclosed
US-4880926-A CRYSTALLIZATION, CAMPHORSULFONIC ACIDS DAIICHI SEIYAKU CO., LTD. (JP) 1989-11-14 US disclosed
EP-0322815-A2 Propoxybenzene derivatives and process for preparing the same DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1989-07-05 EP disclosed
EP-0304684-A1 Process for the preparation of benzoxazine derivatives DAIICHI SEIYAKU CO., LTD. (JP) 1989-03-01 EP disclosed