SCHEMBL11073040

SCHEMBL11073040

C=Cc1ccc(CCl)c(CCl)c1

nearest known ligand 0.43

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.43
TDP1 Q9NUW8 2/20 0.35
TP53 P04637 1/20 0.35
TRPA1 O75762 1/20 0.34
TSHR P16473 1/20 0.33
CHRNB2 P17787 1/20 0.31
CHRNB4 P30926 1/20 0.31
CHRNA3 P32297 1/20 0.31
CHRNA7 P36544 1/20 0.31
CHRNA4 P43681 1/20 0.31
MAPT P10636 1/20 0.31
PKM P14618 1/20 0.31
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9652250 0.88 ALDH1A1 (0.37) ALDH1A1TDP1TP53TRPA1CHRNB2
SCHEMBL19066574 0.88 ALDH1A1 (0.37) ALDH1A1TDP1TP53TRPA1MAPT
SCHEMBL810422 0.88 TDP1 (0.39) ALDH1A1TDP1TP53TRPA1CHRNB2
SCHEMBL810179 0.85 ALDH1A1 (0.34) ALDH1A1TDP1TP53TRPA1CHRNB2
SCHEMBL19066593 0.83 ALDH1A1 (0.33) ALDH1A1
SCHEMBL810315 0.83 ALDH1A1 (0.40) ALDH1A1TDP1TP53TRPA1TSHR
SCHEMBL810172 0.83 ALDH1A1 (0.40) ALDH1A1TDP1TP53TRPA1TSHR
SCHEMBL809759 0.82 TYR (0.39) ALDH1A1TDP1TP53TRPA1TSHR
SCHEMBL18874549 0.82 TP53 (0.35) ALDH1A1TDP1TP53TRPA1
SCHEMBL809528 0.81 TP53 (0.41) ALDH1A1TDP1TP53TRPA1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4467066-A DIENE-VINYLARENE STAR POLYMER, POLYDIENE, VINYLARENE BLENDS SHELL OIL COMPANY (US) 1984-08-21 US disclosed