SCHEMBL809528

SCHEMBL809528

C=Cc1ccc(C)c(CCl)c1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
ALDH1A1 P00352 3/20 0.39
TRPA1 O75762 1/20 0.35
PON1 P27169 1/20 0.33
MAPT P10636 2/20 0.32
PKM P14618 1/20 0.32
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
SLC6A3 Q01959 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
HDAC8 Q9BY41 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18874549 0.88 TP53 (0.35) TP53TDP1ALDH1A1TRPA1TAAR1
SCHEMBL809920 0.85 TP53 (0.38) TP53TDP1ALDH1A1TRPA1MAPT
SCHEMBL26048868 0.84 TDP1 (0.41) TP53TDP1ALDH1A1TRPA1MAPT
SCHEMBL29467225 0.84 TP53 (0.41) TP53TDP1ALDH1A1TRPA1PON1
SCHEMBL809833 0.84 TP53 (0.41) TP53TDP1ALDH1A1TRPA1PON1
SCHEMBL2313482 0.82 TDP1 (0.42) TP53TDP1ALDH1A1TRPA1MAPT
SCHEMBL11073040 0.81 ALDH1A1 (0.43) TP53TDP1ALDH1A1TRPA1MAPT
SCHEMBL810292 0.80 TP53 (0.41) TP53TDP1ALDH1A1TRPA1MAPT
SCHEMBL25572772 0.80 TP53 (0.41) TP53TDP1ALDH1A1TRPA1MAPT
SCHEMBL810422 0.78 TDP1 (0.39) TP53TDP1ALDH1A1TRPA1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012015977-A3 HIGHLY PORTABLE AND STABLE WORK STATION HERSCHLER MATTHEW B (US) 2012-05-10 WO disclosed
EP-2192645-B1 SEPARATION MEMBRANE FOR DIRECT LIQUID FUEL CELL AND METHOD FOR PRODUCING THE SAME TOKUYAMA CORP (JP) 2011-11-30 EP disclosed
US-20110250525-A1 SEPARATION MEMBRANE FOR DIRECT LIQUID FUEL CELL AND METHOD FOR PRODUCING THE SAME TOKUYAMA CORPORATION (JP) 2011-10-13 US disclosed
EP-2192645-A1 SEPARATION MEMBRANE FOR DIRECT LIQUID FUEL CELL AND METHOD FOR PRODUCING THE SAME Tokuyama Corporation (JP) 2010-06-02 EP disclosed
US-5138001-A Optical disc substrates; low birefringence, heat and moisture absorption resistance, high transparency TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1992-08-11 US disclosed
EP-0415729-A2 Vinylphenyl compound, process for the production thereof, polymerizable composition containing same, and crosslinked polymer formed therefrom TOKUYAMA SODA KABUSHIKI KAISHA (JP) 1991-03-06 EP disclosed
US-4074035-A ISOBUTYLENE AND PARA AND META CHLOROMETHYL STYRENE EXXON RESEARCH & ENGINEERING CO. (US) 1978-02-14 US disclosed
US-4070295-A Sulfone copolymeric additive for hydrocarbon oils EXXON RESEARCH AND ENGINEERING COMPANY (US) 1978-01-24 US disclosed
US-4048425-A ACRYLIC ESTERS, MONO-OLEFINS EXXON RESEARCH AND ENGINEERING COMPANY (US) 1977-09-13 US disclosed
US-4014662-A ETHYLENE POLYMERS EXXON RESEARCH AND ENGINEERING COMPANY (US) 1977-03-29 US disclosed