SCHEMBL11073075

SCHEMBL11073075

CN(C)c1ccc(C2OC(=O)c3ccccc32)c(Cl)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
MAPT P10636 4/20 0.39
NPSR1 Q6W5P4 3/20 0.39
TDP1 Q9NUW8 3/20 0.39
HTT P42858 2/20 0.39
LMNA P02545 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
MEN1 O00255 2/20 0.39
GAA P10253 2/20 0.39
HPGD P15428 2/20 0.39
KMT2A Q03164 2/20 0.39
GALR2 O43603 1/20 0.39
NSD2 O96028 1/20 0.39
MAPK1 P28482 1/20 0.39
RAB9A P51151 1/20 0.39
CGAS Q8N884 2/20 0.38
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10690177 0.92 ALDH1A1 (0.38) ALDH1A1MAPTNPSR1TDP1HTT
SCHEMBL11070253 0.87 ALDH1A1 (0.47) ALDH1A1MAPTNPSR1TDP1HTT
SCHEMBL11073268 0.85 ALDH1A1 (0.43) ALDH1A1MAPTNPSR1TDP1HTT
SCHEMBL11073520 0.83 ALDH1A1 (0.40) ALDH1A1MAPTNPSR1TDP1HTT
SCHEMBL11073265 0.81 ALDH1A1 (0.44) ALDH1A1MAPTNPSR1TDP1LMNA
SCHEMBL11070254 0.81 LMNA (0.45) ALDH1A1MAPTNPSR1TDP1HTT
SCHEMBL11073477 0.79 ALDH1A1 (0.42) ALDH1A1MAPTNPSR1SMN1; SMN2L3MBTL1
SCHEMBL9617635 0.79 ALDH1A1 (0.41) ALDH1A1MAPTNPSR1TDP1LMNA
SCHEMBL30422274 0.79 ALDH1A1 (0.41) ALDH1A1MAPTNPSR1TDP1LMNA
SCHEMBL10441515 0.78 ALDH1A1 (0.38) ALDH1A1MAPTNPSR1TDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4443614-A LEUCO DYES, PHTHALEIN DYES, INDICATORS KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1984-04-17 US disclosed
US-4439610-A FROM AMINES AND PHTHALIDES, MULTISTAGE KANZAKI PAPER MANUFACTURING COMPANY, LTD. (JP) 1984-03-27 US disclosed
US-4323700-A OXIDIZING 3-PHENYL PHTHACIDE PERIVATIVES KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1982-04-06 US disclosed
US-4045458-A FRIEDEL-CRAFTS CATALYSTS KANZAKI PAPER MANUFACTURING CO., LTD. (JA) 1977-08-30 US disclosed