Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 17/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 11/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 7/20 | 0.47 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11069986 | 0.91 | OPRM1 (0.48) | OPRM1OPRK1OPRD1OPRL1DRD2 | |
| SCHEMBL11068794 | 0.91 | OPRM1 (0.46) | OPRM1OPRK1OPRD1DRD2DRD3 | |
| SCHEMBL11073734 | 0.90 | OPRM1 (0.47) | OPRM1OPRK1OPRD1DRD2DRD3 | |
| SCHEMBL11074463 | 0.89 | OPRM1 (0.52) | OPRM1OPRK1OPRD1DRD2DRD3 | |
| SCHEMBL11069665 | 0.88 | OPRM1 (0.49) | OPRM1OPRK1OPRD1OPRL1DRD2 | |
| SCHEMBL11075957 | 0.87 | OPRM1 (0.50) | OPRM1OPRK1OPRD1OPRL1DRD2 | |
| SCHEMBL11074455 | 0.86 | OPRM1 (0.48) | OPRM1OPRK1OPRD1DRD2DRD3 | |
| SCHEMBL11074453 | 0.85 | OPRM1 (0.43) | OPRM1OPRK1OPRD1DRD2DRD3 | |
| SCHEMBL11070020 | 0.84 | OPRM1 (0.49) | OPRM1OPRL1GRIN2B | |
| SCHEMBL11070074 | 0.82 | OPRM1 (0.45) | OPRM1OPRK1OPRD1OPRL1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |