Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.49 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.47 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 5/20 | 0.46 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11075825 | 0.89 | OPRM1 (0.51) | OPRM1OPRL1BCHEKDM1AMAOB | |
| SCHEMBL11073158 | 0.84 | OPRM1 (0.50) | OPRM1OPRL1GRIN2B | |
| SCHEMBL11076041 | 0.81 | BCHE (0.44) | OPRM1OPRL1BCHEKDM1AMAOB | |
| SCHEMBL11069896 | 0.79 | OPRM1 (0.43) | OPRM1OPRL1BCHEKDM1AMAOB | |
| SCHEMBL11079938 | 0.79 | OPRL1 (0.46) | OPRM1OPRL1LTB4RLTB4R2GRIN2B | |
| SCHEMBL11078301 | 0.78 | OPRL1 (0.58) | OPRM1OPRL1GRIN2B | |
| SCHEMBL11075823 | 0.78 | OPRM1 (0.49) | OPRM1OPRL1BCHEKDM1AALOX5 | |
| Ethylbenzene SCHEMBL11070027 | 0.77 | OPRM1 (0.51) | OPRM1OPRL1BCHEKDM1AMAOB | |
| SCHEMBL22112018 | 0.77 | OPRL1 (0.56) | OPRM1OPRL1BCHEKDM1AMAOB | |
| SCHEMBL11074085 | 0.77 | ALOX5 (0.56) | OPRM1OPRL1LTB4RLTB4R2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |