Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 4/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.37 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28068560 | 0.92 | CSNK1E (0.41) | ALDH1A1CSNK1ENPC1JAK2RAB9A | |
| SCHEMBL2493913 | 0.92 | CSNK1E (0.41) | ALDH1A1CSNK1ENPC1JAK2RAB9A | |
| SCHEMBL571119 | 0.92 | CSNK1E (0.41) | ALDH1A1CSNK1ENPC1JAK2RAB9A | |
| SCHEMBL30691822 | 0.90 | SIGMAR1 (0.42) | ALDH1A1CSNK1ENPC1JAK2RAB9A | |
| SCHEMBL3457890 | 0.86 | ALDH1A1 (0.46) | ALDH1A1KDM4ECSNK1ENPC1JAK2 | |
| SCHEMBL22483462 | 0.86 | CYP2C19 (0.39) | ALDH1A1KDM4EHTTCSNK1ENPC1 | |
| SCHEMBL28737807 | 0.84 | ALDH1A1 (0.47) | ALDH1A1KDM4EHTTCSNK1ENPC1 | |
| SCHEMBL11232615 | 0.82 | CYP17A1 (0.40) | ALDH1A1GAAKDM4EHTTNPC1 | |
| SCHEMBL7127555 | 0.82 | KDM4A (0.44) | KDM4AKDM2AALDH1A1GAAHDAC11 | |
| SCHEMBL29720594 | 0.81 | ALDH1A1 (0.39) | ALDH1A1GAAKDM4ELMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0047261-B1 | STABILISED COMPOSITIONS CONTAINING BEHAVIOUR MODIFYING COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-06-20 | — | — | EP | disclosed |