Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 10/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 9/20 | 0.39 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11073887 | 0.94 | SLC18A3 (0.40) | OPRM1OPRL1SLC18A3OPRK1SIGMAR1 | |
| SCHEMBL11069131 | 0.91 | SLC18A3 (0.40) | OPRM1OPRL1SLC18A3OPRK1SIGMAR1 | |
| SCHEMBL11069431 | 0.87 | OPRM1 (0.36) | OPRM1OPRL1SLC18A3OPRK1SIGMAR1 | |
| SCHEMBL11070591 | 0.87 | OPRM1 (0.41) | OPRM1OPRL1SLC18A3KMT2A | |
| SCHEMBL11065844 | 0.87 | OPRM1 (0.34) | OPRM1OPRL1OPRK1KCNH2ALDH1A1 | |
| SCHEMBL11070322 | 0.85 | SLC18A3 (0.40) | OPRM1OPRL1SLC18A3OPRK1SIGMAR1 | |
| SCHEMBL11073656 | 0.83 | SLC18A3 (0.35) | OPRM1OPRL1SLC18A3OPRK1SIGMAR1 | |
| SCHEMBL11075013 | 0.81 | OPRM1 (0.42) | OPRM1OPRL1SLC18A3OPRK1SIGMAR1 | |
| SCHEMBL11077368 | 0.80 | GRIN2B (0.42) | OPRM1OPRL1SLC18A3OPRK1SIGMAR1 | |
| SCHEMBL11070288 | 0.80 | SLC6A4 (0.33) | OPRK1KCNH2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |