Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 11/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 6/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11073938 | 0.88 | GRIN2B (0.37) | SLC18A3OPRM1OPRL1OPRK1OPRD1 | |
| SCHEMBL11073838 | 0.86 | KCNN4 (0.32) | — | |
| SCHEMBL11069131 | 0.84 | SLC18A3 (0.40) | SLC18A3OPRM1OPRL1OPRK1OPRD1 | |
| SCHEMBL11073256 | 0.83 | OPRM1 (0.39) | SLC18A3OPRM1OPRL1OPRK1SIGMAR1 | |
| SCHEMBL11073887 | 0.83 | SLC18A3 (0.40) | SLC18A3OPRM1OPRL1OPRK1OPRD1 | |
| SCHEMBL11073670 | 0.82 | UTS2R (0.32) | UTS2R | |
| SCHEMBL11068797 | 0.81 | KCNN4 (0.32) | — | |
| SCHEMBL11069431 | 0.81 | OPRM1 (0.36) | SLC18A3OPRM1OPRL1OPRK1OPRD1 | |
| SCHEMBL11070322 | 0.80 | SLC18A3 (0.40) | SLC18A3OPRM1OPRL1OPRK1OPRD1 | |
| Ethylbenzene SCHEMBL11073664 | 0.80 | OPRM1 (0.31) | OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447454-A | Analgetic compounds, compositions and process of treatment | THE UPJOHN COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| US-4113866-A | ANALGETIC COMPOUNDS, COMPOSITIONS AND PROCESS OF TREATMENT | THE UPJOHN COMPANY (US) | 1978-09-12 | — | — | US | disclosed |