Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA4 | P22748 | 3/20 | 0.37 |
| ▸ | CA6 | P23280 | 3/20 | 0.37 |
| ▸ | CA7 | P43166 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11072919 | 0.83 | BRD4 (0.49) | BRD4ALDH1A1GAACA1CA2 | |
| SCHEMBL11065362 | 0.81 | BRD4 (0.55) | BRD4ALDH1A1GAACA1CA2 | |
| SCHEMBL11260515 | 0.79 | BRD4 (0.49) | BRD4ALDH1A1GAACA1CA2 | |
| SCHEMBL11273367 | 0.79 | SMN1; SMN2 (0.45) | BRD4ALDH1A1GAAL3MBTL1CYP3A4 | |
| SCHEMBL11065079 | 0.77 | BRD4 (0.35) | BRD4ALDH1A1GAAL3MBTL1CYP3A4 | |
| SCHEMBL9032885 | 0.76 | BRD4 (0.51) | BRD4ALDH1A1GAACA1CA2 | |
| SCHEMBL1531470 | 0.74 | BRD4 (0.55) | BRD4ALDH1A1GAACA1CA2 | |
| SCHEMBL17184777 | 0.74 | BRD4 (0.62) | BRD4ALDH1A1GAACA1CA2 | |
| SCHEMBL1461817 | 0.71 | POLB (0.59) | BRD4ALDH1A1GAAL3MBTL1CYP3A4 | |
| SCHEMBL328967 | 0.70 | POLB (0.67) | BRD4ALDH1A1GAAL3MBTL1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0020293-B1 | STABILISING COMPOUNDS, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | CIBA-GEIGY AG (CH) | 1984-05-23 | — | — | EP | disclosed |
| US-4309546-A | Piperidino pyrrolidinones | CIBA-GEIGY CORPORATION (US) | 1982-01-05 | — | — | US | disclosed |
| EP-0020293-A1 | Stabilising compounds, process for their preparation and compositions containing them | CIBA-GEIGY AG (CH) | 1980-12-10 | — | — | EP | disclosed |