Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA4 | P22748 | 3/20 | 0.41 |
| ▸ | CA6 | P23280 | 3/20 | 0.41 |
| ▸ | CA7 | P43166 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29129901 | 0.84 | BRD4 (0.54) | BRD4HPGDALDH1A1GAAMAPK1 | |
| SCHEMBL14990930 | 0.82 | BRD4 (0.69) | BRD4HPGDALDH1A1GAACA1 | |
| SCHEMBL3140082 | 0.81 | BRD4 (0.62) | BRD4HPGDALDH1A1GAACA1 | |
| SCHEMBL8271284 | 0.81 | POLB (0.57) | HPGDALDH1A1GAAMAPTMAPK1 | |
| SCHEMBL12667145 | 0.81 | BRD4 (0.62) | BRD4HPGDALDH1A1GAACA1 | |
| SCHEMBL692641 | 0.81 | POLB (0.57) | HPGDALDH1A1GAAMAPTMAPK1 | |
| SCHEMBL12667147 | 0.81 | BRD4 (0.62) | BRD4HPGDALDH1A1GAACA1 | |
| SCHEMBL17445803 | 0.80 | ALDH1A1 (0.45) | ALDH1A1GAAMAPK1POLBSMN1; SMN2 | |
| SCHEMBL8001584 | 0.80 | POLB (0.41) | ALDH1A1MAPTMAPK1POLBSMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL13280491 | 0.80 | POLB (0.55) | HPGDALDH1A1GAAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10420849-B2 | Pyrrolidone derivatives, oligomers and polymers | NANOSYNTHONS LLC (US) | 2019-09-24 | — | — | US | disclosed |
| US-20170246323-A1 | PYRROLIDONE DERIVATIVES, OLIGOMERS AND POLYMERS | NANOSYNTHONS LLC (US) | 2017-08-31 | — | — | US | disclosed |
| EP-3194365-A1 | PYRROLIDONE DERIVATIVES, OLIGOMERS AND POLYMERS | Nanosynthons LLC (US) | 2017-07-26 | — | — | EP | disclosed |
| WO-2016040962-A1 | PYRROLIDONE DERIVATIVES, OLIGOMERS AND POLYMERS | NANOSYNTHONS LLC (US) | 2016-03-17 | — | — | WO | disclosed |
| EP-2289975-B1 | Organopolysiloxane compound and amidoamine compound, and cosmetic preparation | SHINETSU CHEMICAL CO (JP) | 2012-08-22 | — | — | EP | disclosed |
| US-20110052523-A1 | ORGANOPOLYSILOXANE COMPOUND AND AMIDOAMINE COMPOUND, AND COSMETIC PREPARATION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2011-03-03 | — | — | US | disclosed |
| US-20110052523-A1 | ORGANOPOLYSILOXANE COMPOUND AND AMIDOAMINE COMPOUND, AND COSMETIC PREPARATION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2011-03-03 | — | — | US | disclosed |
| EP-2289975-A2 | Organopolysiloxane compound and amidoamine compound, and cosmetic preparation | Shin-Etsu Chemical Co., Ltd. (JP) | 2011-03-02 | — | — | EP | disclosed |
| EP-1781644-B1 | MACROCYCLIC BETA-SECRETASE INHIBITORS | SCHERING CORP (US) | 2008-05-28 | — | — | EP | disclosed |
| EP-1314736-A2 | Silicone monomers and oligomers having a carboxyl functional group thereon | MONA INDUSTRIES, INC. (US) | 2003-05-28 | — | — | EP | disclosed |
| US-6297383-B1 | HAVING AT LEAST ONE PYRROLIDONE-CONTAINING CARBOXYLIC FUNCTIONAL GROUP, AMPHOTERIC | MONA INDUSTRIES, INC. | 2001-10-02 | — | — | US | disclosed |
| EP-0951468-A4 | SILICONE MONOMERS AND OLIGOMERS HAVING A CARBOXYL FUNCTIONAL GROUP THEREON | MONA INDUSTRIES INC (US) | 2001-06-06 | — | — | EP | disclosed |
| US-6093829-A | Silicone monomers and oligomers having a carboxyl functional group thereon | MONA INDUSTRIES, INC. (US) | 2000-07-25 | — | — | US | disclosed |
| EP-0951468-A1 | SILICONE MONOMERS AND OLIGOMERS HAVING A CARBOXYL FUNCTIONAL GROUP THEREON | MONA INDUSTRIES, INC. (US) | 1999-10-27 | — | — | EP | disclosed |
| US-5919938-A | Silicone monomers and oligomers having a carboxyl functional group thereon | MONA INDUSTRIES, INC. (US) | 1999-07-06 | — | — | US | disclosed |
| US-5780639-A | COUPLING AGENTS, ADHESION PROMOTERS, CROSSLINKING AGENTS | MONA INDUSTRIES, INC. (US) | 1998-07-14 | — | — | US | disclosed |
| WO-1998022478-A1 | SILICONE MONOMERS AND OLIGOMERS HAVING A CARBOXYL FUNCTIONAL GROUP THEREON | MONA INDUSTRIES, INC. (US) | 1998-05-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110052523-A1 | ORGANOPOLYSILOXANE COMPOUND AND AMIDOAMINE COMPOUND, AND COSMETIC PREPARATION | H1-3, H1-0, H1-2 | BRD4 3403/4885HPGD 3825/4885ALDH1A1 1460/4885 |
| US-20170246323-A1 | PYRROLIDONE DERIVATIVES, OLIGOMERS AND POLYMERS | POF1B, VGF, RAB5IF | BRD4 3336/4885HPGD 1614/4885ALDH1A1 2436/4885 |
| US-10420849-B2 | Pyrrolidone derivatives, oligomers and polymers | POF1B, VGF, RAB5IF | BRD4 3336/4885HPGD 1614/4885ALDH1A1 2436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.